Interactive Effect of Endurance Exercise and Crude Alcoholic Extract of Magnolia on Liver Interleukin-6, Interleukin-10, Glucose, and Glycogen in Male Rats

BACKGROUND AND OBJECTIVE: Use of effective supplements on physical function in comparison to industrial supplements is important for a lot of sports nutrition scientists. The purpose of this study was to investigate the interactive effect of endurance exercise and crude alcoholic extract of magnolia...

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Autores principales:	P Farzanegi, M Abdi, A Ghanbari-Niaki, R Fathi, M Hedayati
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2012
Materias:	interlukin-6 interleukin-10 liver glycogen crude extract of magnolol endurance training Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/622150a1c447460390bcfb7eb1822693
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spelling	oai:doaj.org-article:622150a1c447460390bcfb7eb18226932021-11-10T08:53:02ZInteractive Effect of Endurance Exercise and Crude Alcoholic Extract of Magnolia on Liver Interleukin-6, Interleukin-10, Glucose, and Glycogen in Male Rats1561-41072251-7170https://doaj.org/article/622150a1c447460390bcfb7eb18226932012-03-01T00:00:00Zhttp://jbums.org/article-1-4043-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Use of effective supplements on physical function in comparison to industrial supplements is important for a lot of sports nutrition scientists. The purpose of this study was to investigate the interactive effect of endurance exercise and crude alcoholic extract of magnolia on interleukin-6, interleukin-10, glucose, and glycogen in male rat liver.METHODS: In this experimental study, twenty one 6-8 week male rats were divided into 3 groups of saline-control, saline training and magnolia training. The training groups ran on treadmill for 8 weeks (60 min/d, 5d/wk at 25 m/min and 0% grade). Magnolia extract and saline in equal volume (2 mg per kg body weight) from the beginning of the second week for 4 weeks (5 days per week) were fed to three groups. Effect of extract on Il-6 and Il-10 were measured with ELISA method, and glucose and glycogen were measured with Colorimetric method. FINDINGS: IL-10 in practice groups (8.23±1.57 pg/ml versus 25.04±3.05 pg/ml) were significantly lower (p=0.0001). While, Il-6 in saline training group (208.43±48 pg/ml) showed a significant increase in compared to control group (151.29± 23.08 pg/ml) (p=0.04). Glucose level (75.14±24.64 mg/dl versus 87.29±15.07 mg/dl) and glycogen level (3.74± 0.6 mg/g versus 4.67±0.51 mg/g liver tissue) in saline training group were significantly lower (p=0.114 and p=0.024, respectively).CONCLUSION: The results of this study showed that the improvement of liver glycogen induced by magnolia could prevent from exercise-induced increase in IL-6.P FarzanegiM AbdiA Ghanbari-NiakiR FathiM HedayatiBabol University of Medical Sciencesarticleinterlukin-6interleukin-10liverglycogencrude extract of magnololendurance trainingMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 14, Iss 2, Pp 22-30 (2012)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	interlukin-6 interleukin-10 liver glycogen crude extract of magnolol endurance training Medicine R Medicine (General) R5-920
spellingShingle	interlukin-6 interleukin-10 liver glycogen crude extract of magnolol endurance training Medicine R Medicine (General) R5-920 P Farzanegi M Abdi A Ghanbari-Niaki R Fathi M Hedayati Interactive Effect of Endurance Exercise and Crude Alcoholic Extract of Magnolia on Liver Interleukin-6, Interleukin-10, Glucose, and Glycogen in Male Rats
description	BACKGROUND AND OBJECTIVE: Use of effective supplements on physical function in comparison to industrial supplements is important for a lot of sports nutrition scientists. The purpose of this study was to investigate the interactive effect of endurance exercise and crude alcoholic extract of magnolia on interleukin-6, interleukin-10, glucose, and glycogen in male rat liver.METHODS: In this experimental study, twenty one 6-8 week male rats were divided into 3 groups of saline-control, saline training and magnolia training. The training groups ran on treadmill for 8 weeks (60 min/d, 5d/wk at 25 m/min and 0% grade). Magnolia extract and saline in equal volume (2 mg per kg body weight) from the beginning of the second week for 4 weeks (5 days per week) were fed to three groups. Effect of extract on Il-6 and Il-10 were measured with ELISA method, and glucose and glycogen were measured with Colorimetric method. FINDINGS: IL-10 in practice groups (8.23±1.57 pg/ml versus 25.04±3.05 pg/ml) were significantly lower (p=0.0001). While, Il-6 in saline training group (208.43±48 pg/ml) showed a significant increase in compared to control group (151.29± 23.08 pg/ml) (p=0.04). Glucose level (75.14±24.64 mg/dl versus 87.29±15.07 mg/dl) and glycogen level (3.74± 0.6 mg/g versus 4.67±0.51 mg/g liver tissue) in saline training group were significantly lower (p=0.114 and p=0.024, respectively).CONCLUSION: The results of this study showed that the improvement of liver glycogen induced by magnolia could prevent from exercise-induced increase in IL-6.
format	article
author	P Farzanegi M Abdi A Ghanbari-Niaki R Fathi M Hedayati
author_facet	P Farzanegi M Abdi A Ghanbari-Niaki R Fathi M Hedayati
author_sort	P Farzanegi
title	Interactive Effect of Endurance Exercise and Crude Alcoholic Extract of Magnolia on Liver Interleukin-6, Interleukin-10, Glucose, and Glycogen in Male Rats
title_short	Interactive Effect of Endurance Exercise and Crude Alcoholic Extract of Magnolia on Liver Interleukin-6, Interleukin-10, Glucose, and Glycogen in Male Rats
title_full	Interactive Effect of Endurance Exercise and Crude Alcoholic Extract of Magnolia on Liver Interleukin-6, Interleukin-10, Glucose, and Glycogen in Male Rats
title_fullStr	Interactive Effect of Endurance Exercise and Crude Alcoholic Extract of Magnolia on Liver Interleukin-6, Interleukin-10, Glucose, and Glycogen in Male Rats
title_full_unstemmed	Interactive Effect of Endurance Exercise and Crude Alcoholic Extract of Magnolia on Liver Interleukin-6, Interleukin-10, Glucose, and Glycogen in Male Rats
title_sort	interactive effect of endurance exercise and crude alcoholic extract of magnolia on liver interleukin-6, interleukin-10, glucose, and glycogen in male rats
publisher	Babol University of Medical Sciences
publishDate	2012
url	https://doaj.org/article/622150a1c447460390bcfb7eb1822693
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Interactive Effect of Endurance Exercise and Crude Alcoholic Extract of Magnolia on Liver Interleukin-6, Interleukin-10, Glucose, and Glycogen in Male Rats

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