Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness
ABSTRACT Despite our extensive knowledge of the genetic regulation of heat shock proteins (HSPs), the evolutionary routes that allow bacteria to adaptively tune their HSP levels and corresponding proteostatic robustness have been explored less. In this report, directed evolution experiments using th...
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Autores principales: | , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/623a01e2ab7646c0bffe2fbedf477587 |
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