Stereoselective synthesis of sulfur-containing β-enaminonitrile derivatives through electrochemical Csp3–H bond oxidative functionalization of acetonitrile
Direct α-functionalization of acetonitrile, a bulk chemical, is usually limited to its enolate chemistry. Here, the authors show an electro-oxidative C(sp3)–H bond functionalization of acetonitrile with thiols to afford tetrasubstituted olefins with high stereoselectivity.
Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2019
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/623b11d9072743f88ab4086b235f1a21 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| Sumario: | Direct α-functionalization of acetonitrile, a bulk chemical, is usually limited to its enolate chemistry. Here, the authors show an electro-oxidative C(sp3)–H bond functionalization of acetonitrile with thiols to afford tetrasubstituted olefins with high stereoselectivity. |
|---|