The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model

Exposure at birth to maternal microbiota has significant effects on offspring health and development. Here, the authors validate a model where inoculation of mice at birth with human vaginal microbiota produces significant effects on offspring health that are further amplified by an unhealthy prenat...

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Autores principales: Eldin Jašarević, Elizabeth M. Hill, Patrick J. Kane, Lindsay Rutt, Trevonn Gyles, Lillian Folts, Kylie D. Rock, Christopher D. Howard, Kathleen E. Morrison, Jacques Ravel, Tracy L. Bale
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/625376c841e540db8eacedfc764d5104
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Sumario:Exposure at birth to maternal microbiota has significant effects on offspring health and development. Here, the authors validate a model where inoculation of mice at birth with human vaginal microbiota produces significant effects on offspring health that are further amplified by an unhealthy prenatal environment.