The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model

Exposure at birth to maternal microbiota has significant effects on offspring health and development. Here, the authors validate a model where inoculation of mice at birth with human vaginal microbiota produces significant effects on offspring health that are further amplified by an unhealthy prenat...

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Autores principales: Eldin Jašarević, Elizabeth M. Hill, Patrick J. Kane, Lindsay Rutt, Trevonn Gyles, Lillian Folts, Kylie D. Rock, Christopher D. Howard, Kathleen E. Morrison, Jacques Ravel, Tracy L. Bale
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/625376c841e540db8eacedfc764d5104
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spelling oai:doaj.org-article:625376c841e540db8eacedfc764d51042021-11-08T11:08:45ZThe composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model10.1038/s41467-021-26634-92041-1723https://doaj.org/article/625376c841e540db8eacedfc764d51042021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26634-9https://doaj.org/toc/2041-1723Exposure at birth to maternal microbiota has significant effects on offspring health and development. Here, the authors validate a model where inoculation of mice at birth with human vaginal microbiota produces significant effects on offspring health that are further amplified by an unhealthy prenatal environment.Eldin JašarevićElizabeth M. HillPatrick J. KaneLindsay RuttTrevonn GylesLillian FoltsKylie D. RockChristopher D. HowardKathleen E. MorrisonJacques RavelTracy L. BaleNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Eldin Jašarević
Elizabeth M. Hill
Patrick J. Kane
Lindsay Rutt
Trevonn Gyles
Lillian Folts
Kylie D. Rock
Christopher D. Howard
Kathleen E. Morrison
Jacques Ravel
Tracy L. Bale
The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model
description Exposure at birth to maternal microbiota has significant effects on offspring health and development. Here, the authors validate a model where inoculation of mice at birth with human vaginal microbiota produces significant effects on offspring health that are further amplified by an unhealthy prenatal environment.
format article
author Eldin Jašarević
Elizabeth M. Hill
Patrick J. Kane
Lindsay Rutt
Trevonn Gyles
Lillian Folts
Kylie D. Rock
Christopher D. Howard
Kathleen E. Morrison
Jacques Ravel
Tracy L. Bale
author_facet Eldin Jašarević
Elizabeth M. Hill
Patrick J. Kane
Lindsay Rutt
Trevonn Gyles
Lillian Folts
Kylie D. Rock
Christopher D. Howard
Kathleen E. Morrison
Jacques Ravel
Tracy L. Bale
author_sort Eldin Jašarević
title The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model
title_short The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model
title_full The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model
title_fullStr The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model
title_full_unstemmed The composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model
title_sort composition of human vaginal microbiota transferred at birth affects offspring health in a mouse model
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/625376c841e540db8eacedfc764d5104
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