Improving antibiotic activity against wound pathogens with manuka honey in vitro.

Following the discovery of synergistic action between oxacillin and manuka honey against methicillin-resistant Staphylococcus aureus, this study was undertaken to search for further synergistic combinations of antibiotics and honey that might have potential in treating wounds. Fifteen antibiotics we...

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Autores principales:	Rowena Jenkins, Rose Cooper
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6259b0921b134342b093337e19181f15
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spelling	oai:doaj.org-article:6259b0921b134342b093337e19181f152021-11-18T08:13:55ZImproving antibiotic activity against wound pathogens with manuka honey in vitro.1932-620310.1371/journal.pone.0045600https://doaj.org/article/6259b0921b134342b093337e19181f152012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23049822/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Following the discovery of synergistic action between oxacillin and manuka honey against methicillin-resistant Staphylococcus aureus, this study was undertaken to search for further synergistic combinations of antibiotics and honey that might have potential in treating wounds. Fifteen antibiotics were tested with and without sublethal concentrations of manuka honey against each of MRSA and Pseudomonas aeruginosa using disc diffusion, broth dilution, E strip, chequerboard titration and growth curves. Five novel antibiotic and manuka honey combinations were found that improved antibacterial effectiveness in vitro and these offer a new avenue of future topical treatments for wound infections caused by these two important pathogens.Rowena JenkinsRose CooperPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 9, p e45600 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Rowena Jenkins Rose Cooper Improving antibiotic activity against wound pathogens with manuka honey in vitro.
description	Following the discovery of synergistic action between oxacillin and manuka honey against methicillin-resistant Staphylococcus aureus, this study was undertaken to search for further synergistic combinations of antibiotics and honey that might have potential in treating wounds. Fifteen antibiotics were tested with and without sublethal concentrations of manuka honey against each of MRSA and Pseudomonas aeruginosa using disc diffusion, broth dilution, E strip, chequerboard titration and growth curves. Five novel antibiotic and manuka honey combinations were found that improved antibacterial effectiveness in vitro and these offer a new avenue of future topical treatments for wound infections caused by these two important pathogens.
format	article
author	Rowena Jenkins Rose Cooper
author_facet	Rowena Jenkins Rose Cooper
author_sort	Rowena Jenkins
title	Improving antibiotic activity against wound pathogens with manuka honey in vitro.
title_short	Improving antibiotic activity against wound pathogens with manuka honey in vitro.
title_full	Improving antibiotic activity against wound pathogens with manuka honey in vitro.
title_fullStr	Improving antibiotic activity against wound pathogens with manuka honey in vitro.
title_full_unstemmed	Improving antibiotic activity against wound pathogens with manuka honey in vitro.
title_sort	improving antibiotic activity against wound pathogens with manuka honey in vitro.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/6259b0921b134342b093337e19181f15
work_keys_str_mv	AT rowenajenkins improvingantibioticactivityagainstwoundpathogenswithmanukahoneyinvitro AT rosecooper improvingantibioticactivityagainstwoundpathogenswithmanukahoneyinvitro
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Improving antibiotic activity against wound pathogens with manuka honey in vitro.

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