Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis

The single-cell gene expression changes during spinal cord formation and neurogenesis in mice are unclear. Here, the authors use a HES5 reporter to live image, then mathematically model, oscillations in single cells in presumed progenitors and neurons of the developing spinal cord.

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Detalles Bibliográficos
Autores principales: Cerys S. Manning, Veronica Biga, James Boyd, Jochen Kursawe, Bodvar Ymisson, David G. Spiller, Christopher M. Sanderson, Tobias Galla, Magnus Rattray, Nancy Papalopulu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/625df354e8904d6d8d48ca404cd12312
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