The 5′UTR in human adenoviruses: leader diversity in late gene expression

The 5′UTR in human adenoviruses: leader diversity in late gene expression

Abstract Human adenoviruses (HAdVs) shut down host cellular cap-dependent mRNA translation while initiating the translation of viral late mRNAs in a cap-independent manner. HAdV 5′ untranslated regions (5′UTRs) are crucial for cap-independent initiation, and influence mRNA localization and stability...

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Autores principales: Mirja Ramke, Jeong Yoon Lee, David W. Dyer, Donald Seto, Jaya Rajaiya, James Chodosh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/62689b862cdf49849eb21e631744d10e
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