Efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations

Emilio Rintaro Suzuki Jr, Cibele Lima Belico SuzukiInstituto de Olhos Pampulha, Belo, Horizonte, Minas Gerais, BrazilAbstract: Travoprost is a prostaglandin analog used in the management of glaucoma and ocular hypertension for reducing intraocular pressure (IOP). The IOP-lowering efficacy of travopr...

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Autores principales:	Emilio Rintaro Suzuki Jr, Cibele Lima Belico Suzuki
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/626b14f5053a4f129822e53b31e427a7
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spelling	oai:doaj.org-article:626b14f5053a4f129822e53b31e427a72021-12-02T06:17:24ZEfficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations1177-54671177-5483https://doaj.org/article/626b14f5053a4f129822e53b31e427a72010-10-01T00:00:00Zhttp://www.dovepress.com/efficacy-and-safety-of-travoprost-alone-or-in-combination-with-other-a-a5449https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Emilio Rintaro Suzuki Jr, Cibele Lima Belico SuzukiInstituto de Olhos Pampulha, Belo, Horizonte, Minas Gerais, BrazilAbstract: Travoprost is a prostaglandin analog used in the management of glaucoma and ocular hypertension for reducing intraocular pressure (IOP). The IOP-lowering efficacy of travoprost has been shown to be similar to that of other prostaglandins, including latanoprost and bimatoprost. When compared with fixed combinations of timolol and either latanoprost or dorzolamide, travoprost alone can reduce mean IOP in a similar or superior manner. Concomitant therapy of travoprost and timolol can reach even greater IOP reductions than fixed combinations at some time points, but with no difference in the early morning, when IOP is usually higher. In addition, the long duration of action of travoprost can also provide better control of IOP fluctuation, probably due to its stronger prostaglandin F receptor mechanism. The side effects of travoprost do not represent a risk to the vision or health of the patient. The proven efficacy and safety combined with convenient once-daily dosing for travoprost increases patient compliance with treatment for glaucoma.Keywords: travoprost, prostaglandin, glaucoma Emilio Rintaro Suzuki JrCibele Lima Belico SuzukiDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 1165-1171 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Emilio Rintaro Suzuki Jr Cibele Lima Belico Suzuki Efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations
description	Emilio Rintaro Suzuki Jr, Cibele Lima Belico SuzukiInstituto de Olhos Pampulha, Belo, Horizonte, Minas Gerais, BrazilAbstract: Travoprost is a prostaglandin analog used in the management of glaucoma and ocular hypertension for reducing intraocular pressure (IOP). The IOP-lowering efficacy of travoprost has been shown to be similar to that of other prostaglandins, including latanoprost and bimatoprost. When compared with fixed combinations of timolol and either latanoprost or dorzolamide, travoprost alone can reduce mean IOP in a similar or superior manner. Concomitant therapy of travoprost and timolol can reach even greater IOP reductions than fixed combinations at some time points, but with no difference in the early morning, when IOP is usually higher. In addition, the long duration of action of travoprost can also provide better control of IOP fluctuation, probably due to its stronger prostaglandin F receptor mechanism. The side effects of travoprost do not represent a risk to the vision or health of the patient. The proven efficacy and safety combined with convenient once-daily dosing for travoprost increases patient compliance with treatment for glaucoma.Keywords: travoprost, prostaglandin, glaucoma
format	article
author	Emilio Rintaro Suzuki Jr Cibele Lima Belico Suzuki
author_facet	Emilio Rintaro Suzuki Jr Cibele Lima Belico Suzuki
author_sort	Emilio Rintaro Suzuki Jr
title	Efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations
title_short	Efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations
title_full	Efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations
title_fullStr	Efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations
title_full_unstemmed	Efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations
title_sort	efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/626b14f5053a4f129822e53b31e427a7
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Efficacy and safety of travoprost alone or in combination with other agents for glaucoma and ocular hypertension: patient considerations

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