Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme

The current model for B-family DNA polymerases in archaea is one of single-subunit enzymes in contrast to the multi-subunit complexes in eukaryotes. Here the authors show that PolB1 fromSulfolobus solfataricusexists as a heterotrimeric complex in cell extracts.

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Autores principales:	Jiangyu Yan, Thomas R. Beattie, Adriana L. Rojas, Kelly Schermerhorn, Tamzin Gristwood, Jonathan C. Trinidad, Sonja V. Albers, Pietro Roversi, Andrew F. Gardner, Nicola G. A. Abrescia, Stephen D. Bell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/627c7d9ffa8c4d6aa1b8ab4ad90d0baa
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spelling	oai:doaj.org-article:627c7d9ffa8c4d6aa1b8ab4ad90d0baa2021-12-02T17:06:15ZIdentification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme10.1038/ncomms150752041-1723https://doaj.org/article/627c7d9ffa8c4d6aa1b8ab4ad90d0baa2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15075https://doaj.org/toc/2041-1723The current model for B-family DNA polymerases in archaea is one of single-subunit enzymes in contrast to the multi-subunit complexes in eukaryotes. Here the authors show that PolB1 fromSulfolobus solfataricusexists as a heterotrimeric complex in cell extracts.Jiangyu YanThomas R. BeattieAdriana L. RojasKelly SchermerhornTamzin GristwoodJonathan C. TrinidadSonja V. AlbersPietro RoversiAndrew F. GardnerNicola G. A. AbresciaStephen D. BellNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiangyu Yan Thomas R. Beattie Adriana L. Rojas Kelly Schermerhorn Tamzin Gristwood Jonathan C. Trinidad Sonja V. Albers Pietro Roversi Andrew F. Gardner Nicola G. A. Abrescia Stephen D. Bell Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme
description	The current model for B-family DNA polymerases in archaea is one of single-subunit enzymes in contrast to the multi-subunit complexes in eukaryotes. Here the authors show that PolB1 fromSulfolobus solfataricusexists as a heterotrimeric complex in cell extracts.
format	article
author	Jiangyu Yan Thomas R. Beattie Adriana L. Rojas Kelly Schermerhorn Tamzin Gristwood Jonathan C. Trinidad Sonja V. Albers Pietro Roversi Andrew F. Gardner Nicola G. A. Abrescia Stephen D. Bell
author_facet	Jiangyu Yan Thomas R. Beattie Adriana L. Rojas Kelly Schermerhorn Tamzin Gristwood Jonathan C. Trinidad Sonja V. Albers Pietro Roversi Andrew F. Gardner Nicola G. A. Abrescia Stephen D. Bell
author_sort	Jiangyu Yan
title	Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme
title_short	Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme
title_full	Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme
title_fullStr	Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme
title_full_unstemmed	Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme
title_sort	identification and characterization of a heterotrimeric archaeal dna polymerase holoenzyme
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/627c7d9ffa8c4d6aa1b8ab4ad90d0baa
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Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme

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