In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation

Homologous recombination uses a template to accurately repair DNA double-strand breaks and stalled replication forks to maintain genome stability. Here authors use electron microscopy to investigate the role of Rad54 in homology search and synaptic complex formation.

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Autores principales: Eliana Moreira Tavares, William Douglass Wright, Wolf-Dietrich Heyer, Eric Le Cam, Pauline Dupaigne
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/6285e38938b646c09006dc0d1a12710a
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spelling oai:doaj.org-article:6285e38938b646c09006dc0d1a12710a2021-12-02T15:35:04ZIn vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation10.1038/s41467-019-12082-z2041-1723https://doaj.org/article/6285e38938b646c09006dc0d1a12710a2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12082-zhttps://doaj.org/toc/2041-1723Homologous recombination uses a template to accurately repair DNA double-strand breaks and stalled replication forks to maintain genome stability. Here authors use electron microscopy to investigate the role of Rad54 in homology search and synaptic complex formation.Eliana Moreira TavaresWilliam Douglass WrightWolf-Dietrich HeyerEric Le CamPauline DupaigneNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Eliana Moreira Tavares
William Douglass Wright
Wolf-Dietrich Heyer
Eric Le Cam
Pauline Dupaigne
In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation
description Homologous recombination uses a template to accurately repair DNA double-strand breaks and stalled replication forks to maintain genome stability. Here authors use electron microscopy to investigate the role of Rad54 in homology search and synaptic complex formation.
format article
author Eliana Moreira Tavares
William Douglass Wright
Wolf-Dietrich Heyer
Eric Le Cam
Pauline Dupaigne
author_facet Eliana Moreira Tavares
William Douglass Wright
Wolf-Dietrich Heyer
Eric Le Cam
Pauline Dupaigne
author_sort Eliana Moreira Tavares
title In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation
title_short In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation
title_full In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation
title_fullStr In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation
title_full_unstemmed In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation
title_sort in vitro role of rad54 in rad51-ssdna filament-dependent homology search and synaptic complexes formation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/6285e38938b646c09006dc0d1a12710a
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