In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation
Homologous recombination uses a template to accurately repair DNA double-strand breaks and stalled replication forks to maintain genome stability. Here authors use electron microscopy to investigate the role of Rad54 in homology search and synaptic complex formation.
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Nature Portfolio
2019
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oai:doaj.org-article:6285e38938b646c09006dc0d1a12710a2021-12-02T15:35:04ZIn vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation10.1038/s41467-019-12082-z2041-1723https://doaj.org/article/6285e38938b646c09006dc0d1a12710a2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12082-zhttps://doaj.org/toc/2041-1723Homologous recombination uses a template to accurately repair DNA double-strand breaks and stalled replication forks to maintain genome stability. Here authors use electron microscopy to investigate the role of Rad54 in homology search and synaptic complex formation.Eliana Moreira TavaresWilliam Douglass WrightWolf-Dietrich HeyerEric Le CamPauline DupaigneNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019) |
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Science Q Eliana Moreira Tavares William Douglass Wright Wolf-Dietrich Heyer Eric Le Cam Pauline Dupaigne In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation |
description |
Homologous recombination uses a template to accurately repair DNA double-strand breaks and stalled replication forks to maintain genome stability. Here authors use electron microscopy to investigate the role of Rad54 in homology search and synaptic complex formation. |
format |
article |
author |
Eliana Moreira Tavares William Douglass Wright Wolf-Dietrich Heyer Eric Le Cam Pauline Dupaigne |
author_facet |
Eliana Moreira Tavares William Douglass Wright Wolf-Dietrich Heyer Eric Le Cam Pauline Dupaigne |
author_sort |
Eliana Moreira Tavares |
title |
In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation |
title_short |
In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation |
title_full |
In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation |
title_fullStr |
In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation |
title_full_unstemmed |
In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation |
title_sort |
in vitro role of rad54 in rad51-ssdna filament-dependent homology search and synaptic complexes formation |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/6285e38938b646c09006dc0d1a12710a |
work_keys_str_mv |
AT elianamoreiratavares invitroroleofrad54inrad51ssdnafilamentdependenthomologysearchandsynapticcomplexesformation AT williamdouglasswright invitroroleofrad54inrad51ssdnafilamentdependenthomologysearchandsynapticcomplexesformation AT wolfdietrichheyer invitroroleofrad54inrad51ssdnafilamentdependenthomologysearchandsynapticcomplexesformation AT ericlecam invitroroleofrad54inrad51ssdnafilamentdependenthomologysearchandsynapticcomplexesformation AT paulinedupaigne invitroroleofrad54inrad51ssdnafilamentdependenthomologysearchandsynapticcomplexesformation |
_version_ |
1718386659296280576 |