Z-ring membrane anchors associate with cell wall synthases to initiate bacterial cell division

Proteins FtsZ, ZipA, and either PBP1A or PBP1B are required for the synthesis of preseptal peptidoglycan at the future cell division site in E. coli. Here, Pazos et al. provide evidence that ZipA and FtsA-FtsN connect the cytosolic FtsZ ring with the membrane-anchored PBPs.

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Detalles Bibliográficos
Autores principales: Manuel Pazos, Katharina Peters, Mercedes Casanova, Pilar Palacios, Michael VanNieuwenhze, Eefjan Breukink, Miguel Vicente, Waldemar Vollmer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6285ee4d3fe44f16961d2d40a141e1be
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Sumario:Proteins FtsZ, ZipA, and either PBP1A or PBP1B are required for the synthesis of preseptal peptidoglycan at the future cell division site in E. coli. Here, Pazos et al. provide evidence that ZipA and FtsA-FtsN connect the cytosolic FtsZ ring with the membrane-anchored PBPs.