Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress

Radiotherapy has the potential to induce immunogenic cell death (ICD), however radiation-induced immune responses are often limited. Here the authors design gadolinium-based nanoscale coordination polymers to amplify radiation-mediated oxidative stress, promoting ICD and anti-tumor immune responses.

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Detalles Bibliográficos
Autores principales: Zhusheng Huang, Yuxiang Wang, Dan Yao, Jinhui Wu, Yiqiao Hu, Ahu Yuan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/628aaa3b1f66483d85dd2ded4302887a
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Sumario:Radiotherapy has the potential to induce immunogenic cell death (ICD), however radiation-induced immune responses are often limited. Here the authors design gadolinium-based nanoscale coordination polymers to amplify radiation-mediated oxidative stress, promoting ICD and anti-tumor immune responses.