Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress

Radiotherapy has the potential to induce immunogenic cell death (ICD), however radiation-induced immune responses are often limited. Here the authors design gadolinium-based nanoscale coordination polymers to amplify radiation-mediated oxidative stress, promoting ICD and anti-tumor immune responses.

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Autores principales:	Zhusheng Huang, Yuxiang Wang, Dan Yao, Jinhui Wu, Yiqiao Hu, Ahu Yuan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/628aaa3b1f66483d85dd2ded4302887a
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spelling	oai:doaj.org-article:628aaa3b1f66483d85dd2ded4302887a2021-12-02T15:16:22ZNanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress10.1038/s41467-020-20243-82041-1723https://doaj.org/article/628aaa3b1f66483d85dd2ded4302887a2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20243-8https://doaj.org/toc/2041-1723Radiotherapy has the potential to induce immunogenic cell death (ICD), however radiation-induced immune responses are often limited. Here the authors design gadolinium-based nanoscale coordination polymers to amplify radiation-mediated oxidative stress, promoting ICD and anti-tumor immune responses.Zhusheng HuangYuxiang WangDan YaoJinhui WuYiqiao HuAhu YuanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhusheng Huang Yuxiang Wang Dan Yao Jinhui Wu Yiqiao Hu Ahu Yuan Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress
description	Radiotherapy has the potential to induce immunogenic cell death (ICD), however radiation-induced immune responses are often limited. Here the authors design gadolinium-based nanoscale coordination polymers to amplify radiation-mediated oxidative stress, promoting ICD and anti-tumor immune responses.
format	article
author	Zhusheng Huang Yuxiang Wang Dan Yao Jinhui Wu Yiqiao Hu Ahu Yuan
author_facet	Zhusheng Huang Yuxiang Wang Dan Yao Jinhui Wu Yiqiao Hu Ahu Yuan
author_sort	Zhusheng Huang
title	Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress
title_short	Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress
title_full	Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress
title_fullStr	Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress
title_full_unstemmed	Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress
title_sort	nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/628aaa3b1f66483d85dd2ded4302887a
work_keys_str_mv	AT zhushenghuang nanoscalecoordinationpolymersinduceimmunogeniccelldeathbyamplifyingradiationtherapymediatedoxidativestress AT yuxiangwang nanoscalecoordinationpolymersinduceimmunogeniccelldeathbyamplifyingradiationtherapymediatedoxidativestress AT danyao nanoscalecoordinationpolymersinduceimmunogeniccelldeathbyamplifyingradiationtherapymediatedoxidativestress AT jinhuiwu nanoscalecoordinationpolymersinduceimmunogeniccelldeathbyamplifyingradiationtherapymediatedoxidativestress AT yiqiaohu nanoscalecoordinationpolymersinduceimmunogeniccelldeathbyamplifyingradiationtherapymediatedoxidativestress AT ahuyuan nanoscalecoordinationpolymersinduceimmunogeniccelldeathbyamplifyingradiationtherapymediatedoxidativestress
_version_	1718387509557198848

Nanoscale coordination polymers induce immunogenic cell death by amplifying radiation therapy mediated oxidative stress

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