Tumors of the eye and ocular adnexa at the Philippine Eye Research Institute: a 10-year review

Rolando Enrique D Domingo,1,2 Lilibeth E Manganip,1 Rolando M Castro1 1Philippine Eye Research Institute, National Institutes of Health, University of the Philippines, Manila, Philippines; 2Department of Ophthalmology and Visual Sciences, University of the Philippines College of Medicine &ndash...

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Autores principales:	Domingo RE, Manganip LE, Castro RM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/62963a4b06d542c98efb01b7814e6910
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spelling	oai:doaj.org-article:62963a4b06d542c98efb01b7814e69102021-12-02T12:06:01ZTumors of the eye and ocular adnexa at the Philippine Eye Research Institute: a 10-year review1177-5483https://doaj.org/article/62963a4b06d542c98efb01b7814e69102015-07-01T00:00:00Zhttp://www.dovepress.com/tumors-of-the-eye-and-ocular-adnexa-at-the-philippine-eye-research-ins-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Rolando Enrique D Domingo,1,2 Lilibeth E Manganip,1 Rolando M Castro1 1Philippine Eye Research Institute, National Institutes of Health, University of the Philippines, Manila, Philippines; 2Department of Ophthalmology and Visual Sciences, University of the Philippines College of Medicine – Philippine General Hospital, Manila, Philippines Objective: We aimed to identify and describe the clinicopathologic characteristics of tumors of the eye and ocular adnexa at the Philippine Eye Research Institute. Methods: The pathology reports of specimens submitted to the Ocular Pathology Section of the Philippine Eye Research Institute over a 10-year period (2003–2012) were reviewed, and collected data was subjected to descriptive statistical tabulation and analysis. Results: A total of 1,551 histologically confirmed tumors were included. Of these, 254 were from the conjunctiva (155 benign, 99 malignant), 530 from the eyelids (360 benign, 170 malignant), 394 were intraocular tumors (21 benign, 373 malignant), and 373 were from the orbit (231 benign, 142 malignant). Retinoblastoma was the most common tumor of the eye and ocular adnexa in the series, accounting for 43.2% of all malignancies. Squamous cell carcinoma was the most frequent cancer of the conjunctiva, while basal cell carcinoma and sebaceous gland carcinoma were the most common eyelid malignancies. Orbital malignancies had a bimodal age distribution, with rhabdomyosarcoma being most frequent in children, while in adults, lymphoma was most common, followed by lacrimal gland carcinomas. Conclusion: The majority of tumors of the conjunctiva, eyelids, and orbit were benign, while most intraocular tumors were malignant, with retinoblastoma being the most common. Keywords: cancer, ophthalmic, retinoblastoma, clinical characteristicsDomingo REManganip LECastro RMDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 1239-1247 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Domingo RE Manganip LE Castro RM Tumors of the eye and ocular adnexa at the Philippine Eye Research Institute: a 10-year review
description	Rolando Enrique D Domingo,1,2 Lilibeth E Manganip,1 Rolando M Castro1 1Philippine Eye Research Institute, National Institutes of Health, University of the Philippines, Manila, Philippines; 2Department of Ophthalmology and Visual Sciences, University of the Philippines College of Medicine – Philippine General Hospital, Manila, Philippines Objective: We aimed to identify and describe the clinicopathologic characteristics of tumors of the eye and ocular adnexa at the Philippine Eye Research Institute. Methods: The pathology reports of specimens submitted to the Ocular Pathology Section of the Philippine Eye Research Institute over a 10-year period (2003–2012) were reviewed, and collected data was subjected to descriptive statistical tabulation and analysis. Results: A total of 1,551 histologically confirmed tumors were included. Of these, 254 were from the conjunctiva (155 benign, 99 malignant), 530 from the eyelids (360 benign, 170 malignant), 394 were intraocular tumors (21 benign, 373 malignant), and 373 were from the orbit (231 benign, 142 malignant). Retinoblastoma was the most common tumor of the eye and ocular adnexa in the series, accounting for 43.2% of all malignancies. Squamous cell carcinoma was the most frequent cancer of the conjunctiva, while basal cell carcinoma and sebaceous gland carcinoma were the most common eyelid malignancies. Orbital malignancies had a bimodal age distribution, with rhabdomyosarcoma being most frequent in children, while in adults, lymphoma was most common, followed by lacrimal gland carcinomas. Conclusion: The majority of tumors of the conjunctiva, eyelids, and orbit were benign, while most intraocular tumors were malignant, with retinoblastoma being the most common. Keywords: cancer, ophthalmic, retinoblastoma, clinical characteristics
format	article
author	Domingo RE Manganip LE Castro RM
author_facet	Domingo RE Manganip LE Castro RM
author_sort	Domingo RE
title	Tumors of the eye and ocular adnexa at the Philippine Eye Research Institute: a 10-year review
title_short	Tumors of the eye and ocular adnexa at the Philippine Eye Research Institute: a 10-year review
title_full	Tumors of the eye and ocular adnexa at the Philippine Eye Research Institute: a 10-year review
title_fullStr	Tumors of the eye and ocular adnexa at the Philippine Eye Research Institute: a 10-year review
title_full_unstemmed	Tumors of the eye and ocular adnexa at the Philippine Eye Research Institute: a 10-year review
title_sort	tumors of the eye and ocular adnexa at the philippine eye research institute: a 10-year review
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/62963a4b06d542c98efb01b7814e6910
work_keys_str_mv	AT domingore tumorsoftheeyeandocularadnexaatthephilippineeyeresearchinstitutea10yearreview AT manganiple tumorsoftheeyeandocularadnexaatthephilippineeyeresearchinstitutea10yearreview AT castrorm tumorsoftheeyeandocularadnexaatthephilippineeyeresearchinstitutea10yearreview
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Tumors of the eye and ocular adnexa at the Philippine Eye Research Institute: a 10-year review

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