Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation

Multiple myeloma is characterized by high rates of drug resistance and relapse. Here the authors utilize a functional assay to assess the ex vivo drug sensitivity of single multiple myeloma cells based on measuring the mass accumulation rate of individual cells.

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Autores principales:	Arif E. Cetin, Mark M. Stevens, Nicholas L. Calistri, Mariateresa Fulciniti, Selim Olcum, Robert J. Kimmerling, Nikhil C. Munshi, Scott R. Manalis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/629a770514a4473e857f4d9145de3dc2
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spelling	oai:doaj.org-article:629a770514a4473e857f4d9145de3dc22021-12-02T15:38:40ZDetermining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation10.1038/s41467-017-01593-22041-1723https://doaj.org/article/629a770514a4473e857f4d9145de3dc22017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01593-2https://doaj.org/toc/2041-1723Multiple myeloma is characterized by high rates of drug resistance and relapse. Here the authors utilize a functional assay to assess the ex vivo drug sensitivity of single multiple myeloma cells based on measuring the mass accumulation rate of individual cells.Arif E. CetinMark M. StevensNicholas L. CalistriMariateresa FulcinitiSelim OlcumRobert J. KimmerlingNikhil C. MunshiScott R. ManalisNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Arif E. Cetin Mark M. Stevens Nicholas L. Calistri Mariateresa Fulciniti Selim Olcum Robert J. Kimmerling Nikhil C. Munshi Scott R. Manalis Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation
description	Multiple myeloma is characterized by high rates of drug resistance and relapse. Here the authors utilize a functional assay to assess the ex vivo drug sensitivity of single multiple myeloma cells based on measuring the mass accumulation rate of individual cells.
format	article
author	Arif E. Cetin Mark M. Stevens Nicholas L. Calistri Mariateresa Fulciniti Selim Olcum Robert J. Kimmerling Nikhil C. Munshi Scott R. Manalis
author_facet	Arif E. Cetin Mark M. Stevens Nicholas L. Calistri Mariateresa Fulciniti Selim Olcum Robert J. Kimmerling Nikhil C. Munshi Scott R. Manalis
author_sort	Arif E. Cetin
title	Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation
title_short	Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation
title_full	Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation
title_fullStr	Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation
title_full_unstemmed	Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation
title_sort	determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/629a770514a4473e857f4d9145de3dc2
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Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation

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