Association of microalbuminuria with ischemic heart disease in non-diabetic Asian-Indians: A case control study

Context: Microalbuminuria is a known indicator of atherosclerosis and its association with ischemic heart disease (IHD) has been extensively studied in the diabetic population. The significance of urine microalbumin in non-diabetics, however, is yet to be elucidated. Aim: To determine whether an ind...

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Autores principales:	Sowjanya Naha, Kushal Naha, Vinay R Pandit, R Balasubramanian
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2015
Materias:	asian-indian ischemic heart disease microalbuminuria non-diabetic Medicine R
Acceso en línea:	https://doaj.org/article/629af54676ac42e68a42d264f19f062a
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spelling	oai:doaj.org-article:629af54676ac42e68a42d264f19f062a2021-12-02T16:38:07ZAssociation of microalbuminuria with ischemic heart disease in non-diabetic Asian-Indians: A case control study2231-07702249-446410.4103/2231-0770.148501https://doaj.org/article/629af54676ac42e68a42d264f19f062a2015-01-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.148501https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Context: Microalbuminuria is a known indicator of atherosclerosis and its association with ischemic heart disease (IHD) has been extensively studied in the diabetic population. The significance of urine microalbumin in non-diabetics, however, is yet to be elucidated. Aim: To determine whether an independent association exists between microalbuminuria and IHD in non-diabetic Asian-Indians, and the level of microalbuminuria predictive of concomitant IHD. Materials and Methods: A cross-sectional case-control study was conducted between July 2009 and June 2011. Non-diabetic patients undergoing evaluation for IHD were divided into cases and controls, based on the presence or absence of IHD, respectively. Fifty cases and 50 controls were included, and matched by age, sex, smoking habit, hypertension and body-mass index (BMI). Fasting blood glucose (FBG), fasting lipid profile, and urine microalbumin were recorded for all patients. Results: Mean fasting glucose, mean low density lipoprotein (LDL)-cholesterol and mean urine microalbumin were all significantly higher in cases compared to controls. Urine microalbumin was independently associated with IHD, and microalbumin greater than 12.6 mg/g was predictive of IHD (OR: 13.5; 95% CI, 4.6-39.9; P < 0.001). Conclusion: Urine microalbumin is independently associated with IHD in non-diabetics and levels greater than 12.6 mg/g are predictive of IHD.Sowjanya NahaKushal NahaVinay R PanditR BalasubramanianThieme Medical and Scientific Publishers Pvt. Ltd.articleasian-indianischemic heart diseasemicroalbuminurianon-diabeticMedicineRENAvicenna Journal of Medicine, Vol 05, Iss 01, Pp 6-10 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	asian-indian ischemic heart disease microalbuminuria non-diabetic Medicine R
spellingShingle	asian-indian ischemic heart disease microalbuminuria non-diabetic Medicine R Sowjanya Naha Kushal Naha Vinay R Pandit R Balasubramanian Association of microalbuminuria with ischemic heart disease in non-diabetic Asian-Indians: A case control study
description	Context: Microalbuminuria is a known indicator of atherosclerosis and its association with ischemic heart disease (IHD) has been extensively studied in the diabetic population. The significance of urine microalbumin in non-diabetics, however, is yet to be elucidated. Aim: To determine whether an independent association exists between microalbuminuria and IHD in non-diabetic Asian-Indians, and the level of microalbuminuria predictive of concomitant IHD. Materials and Methods: A cross-sectional case-control study was conducted between July 2009 and June 2011. Non-diabetic patients undergoing evaluation for IHD were divided into cases and controls, based on the presence or absence of IHD, respectively. Fifty cases and 50 controls were included, and matched by age, sex, smoking habit, hypertension and body-mass index (BMI). Fasting blood glucose (FBG), fasting lipid profile, and urine microalbumin were recorded for all patients. Results: Mean fasting glucose, mean low density lipoprotein (LDL)-cholesterol and mean urine microalbumin were all significantly higher in cases compared to controls. Urine microalbumin was independently associated with IHD, and microalbumin greater than 12.6 mg/g was predictive of IHD (OR: 13.5; 95% CI, 4.6-39.9; P < 0.001). Conclusion: Urine microalbumin is independently associated with IHD in non-diabetics and levels greater than 12.6 mg/g are predictive of IHD.
format	article
author	Sowjanya Naha Kushal Naha Vinay R Pandit R Balasubramanian
author_facet	Sowjanya Naha Kushal Naha Vinay R Pandit R Balasubramanian
author_sort	Sowjanya Naha
title	Association of microalbuminuria with ischemic heart disease in non-diabetic Asian-Indians: A case control study
title_short	Association of microalbuminuria with ischemic heart disease in non-diabetic Asian-Indians: A case control study
title_full	Association of microalbuminuria with ischemic heart disease in non-diabetic Asian-Indians: A case control study
title_fullStr	Association of microalbuminuria with ischemic heart disease in non-diabetic Asian-Indians: A case control study
title_full_unstemmed	Association of microalbuminuria with ischemic heart disease in non-diabetic Asian-Indians: A case control study
title_sort	association of microalbuminuria with ischemic heart disease in non-diabetic asian-indians: a case control study
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2015
url	https://doaj.org/article/629af54676ac42e68a42d264f19f062a
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Association of microalbuminuria with ischemic heart disease in non-diabetic Asian-Indians: A case control study

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