iStent Trabecular Microbypass Stent Implantation with Phacoemulsification in Patients with Open-Angle Glaucoma: 6-Year Outcomes

Tanner J Ferguson,1 Keegan B Mechels,1 Zachary Dockter,2 Adam Bleeker,2 Mitch Ibach,3 Justin Schweitzer,3 John P Berdahl3 1Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA; 2University of South Dakota Sanford School of Medicine, Sioux Falls, SD, USA; 3Vance Thompson Vision, Sioux Falls, SD,...

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Autores principales:	Ferguson TJ, Mechels KB, Dockter Z, Bleeker A, Ibach M, Schweitzer J, Berdahl JP
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	microinvasive glaucoma surgery migs trabecular micro-bypass stent surgical glaucoma primary open-angle glaucoma Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/62a08b47a796438a9ec2a0d56aeed40c
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spelling	oai:doaj.org-article:62a08b47a796438a9ec2a0d56aeed40c2021-12-02T10:18:39ZiStent Trabecular Microbypass Stent Implantation with Phacoemulsification in Patients with Open-Angle Glaucoma: 6-Year Outcomes1177-5483https://doaj.org/article/62a08b47a796438a9ec2a0d56aeed40c2020-07-01T00:00:00Zhttps://www.dovepress.com/istent-trabecular-microbypass-stent-implantation-with-phacoemulsificat-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Tanner J Ferguson,1 Keegan B Mechels,1 Zachary Dockter,2 Adam Bleeker,2 Mitch Ibach,3 Justin Schweitzer,3 John P Berdahl3 1Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA; 2University of South Dakota Sanford School of Medicine, Sioux Falls, SD, USA; 3Vance Thompson Vision, Sioux Falls, SD, USACorrespondence: Tanner J Ferguson Email tannerferg@gmail.comPurpose: To investigate the long-term safety and efficacy of an iStent trabecular microbypass stent in combination with cataract surgery in eyes with primary open-angle glaucoma (POAG).Setting: Private practice; Sioux Falls, South Dakota.Design: Retrospective, consecutive case series.Methods: This case series included eyes implanted with a single trabecular microbypass stent in combination with phacoemulsification in patients with mild to severe POAG. Data were collected preoperatively and at day 1, week 1, month 1, and up to 6 years postoperatively. Primary outcome measures included mean intraocular pressure (IOP) and number of glaucoma medications. Safety was noted by assessing the incidence of IOP spikes and need for additional surgery.Results: The study comprised 411 eyes. Mean IOP was reduced to 14.9± 4.2 mmHg compared to 18.8± 5.6 mmHg at baseline at 6 years postoperative. The mean number of medications was reduced to 1.2± 1.0 from 1.4± 1.1 at baseline. In eyes with severe stage of disease, there was a mean IOP reduction > 6 mmHg at 6 years postoperative. Eyes with baseline IOP ≥ 18 mmHg achieved a more robust reduction in IOP. Fifteen eyes underwent a secondary glaucoma procedure. There were no intra- or postoperative complications.Conclusion: Trabecular microbypass stent implantation in combination with cataract surgery provides a sustained IOP reduction in eyes with mild-to-severe POAG. The degree of IOP reduction was more significant in eyes with higher baseline IOP and severe stage of disease.Keywords: microinvasive glaucoma surgery, MIGS, trabecular microbypass stent, surgical glaucoma, primary open-angle glaucomaFerguson TJMechels KBDockter ZBleeker AIbach MSchweitzer JBerdahl JPDove Medical Pressarticlemicroinvasive glaucoma surgerymigstrabecular micro-bypass stentsurgical glaucomaprimary open-angle glaucomaOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 1859-1866 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	microinvasive glaucoma surgery migs trabecular micro-bypass stent surgical glaucoma primary open-angle glaucoma Ophthalmology RE1-994
spellingShingle	microinvasive glaucoma surgery migs trabecular micro-bypass stent surgical glaucoma primary open-angle glaucoma Ophthalmology RE1-994 Ferguson TJ Mechels KB Dockter Z Bleeker A Ibach M Schweitzer J Berdahl JP iStent Trabecular Microbypass Stent Implantation with Phacoemulsification in Patients with Open-Angle Glaucoma: 6-Year Outcomes
description	Tanner J Ferguson,1 Keegan B Mechels,1 Zachary Dockter,2 Adam Bleeker,2 Mitch Ibach,3 Justin Schweitzer,3 John P Berdahl3 1Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA; 2University of South Dakota Sanford School of Medicine, Sioux Falls, SD, USA; 3Vance Thompson Vision, Sioux Falls, SD, USACorrespondence: Tanner J Ferguson Email tannerferg@gmail.comPurpose: To investigate the long-term safety and efficacy of an iStent trabecular microbypass stent in combination with cataract surgery in eyes with primary open-angle glaucoma (POAG).Setting: Private practice; Sioux Falls, South Dakota.Design: Retrospective, consecutive case series.Methods: This case series included eyes implanted with a single trabecular microbypass stent in combination with phacoemulsification in patients with mild to severe POAG. Data were collected preoperatively and at day 1, week 1, month 1, and up to 6 years postoperatively. Primary outcome measures included mean intraocular pressure (IOP) and number of glaucoma medications. Safety was noted by assessing the incidence of IOP spikes and need for additional surgery.Results: The study comprised 411 eyes. Mean IOP was reduced to 14.9± 4.2 mmHg compared to 18.8± 5.6 mmHg at baseline at 6 years postoperative. The mean number of medications was reduced to 1.2± 1.0 from 1.4± 1.1 at baseline. In eyes with severe stage of disease, there was a mean IOP reduction > 6 mmHg at 6 years postoperative. Eyes with baseline IOP ≥ 18 mmHg achieved a more robust reduction in IOP. Fifteen eyes underwent a secondary glaucoma procedure. There were no intra- or postoperative complications.Conclusion: Trabecular microbypass stent implantation in combination with cataract surgery provides a sustained IOP reduction in eyes with mild-to-severe POAG. The degree of IOP reduction was more significant in eyes with higher baseline IOP and severe stage of disease.Keywords: microinvasive glaucoma surgery, MIGS, trabecular microbypass stent, surgical glaucoma, primary open-angle glaucoma
format	article
author	Ferguson TJ Mechels KB Dockter Z Bleeker A Ibach M Schweitzer J Berdahl JP
author_facet	Ferguson TJ Mechels KB Dockter Z Bleeker A Ibach M Schweitzer J Berdahl JP
author_sort	Ferguson TJ
title	iStent Trabecular Microbypass Stent Implantation with Phacoemulsification in Patients with Open-Angle Glaucoma: 6-Year Outcomes
title_short	iStent Trabecular Microbypass Stent Implantation with Phacoemulsification in Patients with Open-Angle Glaucoma: 6-Year Outcomes
title_full	iStent Trabecular Microbypass Stent Implantation with Phacoemulsification in Patients with Open-Angle Glaucoma: 6-Year Outcomes
title_fullStr	iStent Trabecular Microbypass Stent Implantation with Phacoemulsification in Patients with Open-Angle Glaucoma: 6-Year Outcomes
title_full_unstemmed	iStent Trabecular Microbypass Stent Implantation with Phacoemulsification in Patients with Open-Angle Glaucoma: 6-Year Outcomes
title_sort	istent trabecular microbypass stent implantation with phacoemulsification in patients with open-angle glaucoma: 6-year outcomes
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/62a08b47a796438a9ec2a0d56aeed40c
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iStent Trabecular Microbypass Stent Implantation with Phacoemulsification in Patients with Open-Angle Glaucoma: 6-Year Outcomes

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