Engineering of a bona fide light-operated calcium channel
Existing optogenetic methods to induce calcium mobilisation lack selectivity and specificity. Here, the authors design and engineer a single-component light-operated calcium channel to provide optical control over calcium signals and calcium-dependent physiological responses: LOCa.
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Main Authors: | Lian He, Liuqing Wang, Hongxiang Zeng, Peng Tan, Guolin Ma, Sisi Zheng, Yaxin Li, Lin Sun, Fei Dou, Stefan Siwko, Yun Huang, Youjun Wang, Yubin Zhou |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/62a2bcdaa2fd4fe79a851bd0dc9573de |
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