Neuronal control of peripheral insulin sensitivity and glucose metabolism
The brain controls peripheral glucose metabolism, for example by modulating hepatic gluconeogenesis or by regulating glucose uptake into brown adipose tissue. Here, the authors review the brain regions, neurons and molecular mechanisms involved in these processes, and discuss their relevance to dise...
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Nature Portfolio
2017
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oai:doaj.org-article:62a98d37c005424dbfdf3e77a01d017e2021-12-02T14:40:34ZNeuronal control of peripheral insulin sensitivity and glucose metabolism10.1038/ncomms152592041-1723https://doaj.org/article/62a98d37c005424dbfdf3e77a01d017e2017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15259https://doaj.org/toc/2041-1723The brain controls peripheral glucose metabolism, for example by modulating hepatic gluconeogenesis or by regulating glucose uptake into brown adipose tissue. Here, the authors review the brain regions, neurons and molecular mechanisms involved in these processes, and discuss their relevance to disease.Johan RuudSophie M. SteculorumJens C. BrüningNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017) |
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Science Q Johan Ruud Sophie M. Steculorum Jens C. Brüning Neuronal control of peripheral insulin sensitivity and glucose metabolism |
description |
The brain controls peripheral glucose metabolism, for example by modulating hepatic gluconeogenesis or by regulating glucose uptake into brown adipose tissue. Here, the authors review the brain regions, neurons and molecular mechanisms involved in these processes, and discuss their relevance to disease. |
format |
article |
author |
Johan Ruud Sophie M. Steculorum Jens C. Brüning |
author_facet |
Johan Ruud Sophie M. Steculorum Jens C. Brüning |
author_sort |
Johan Ruud |
title |
Neuronal control of peripheral insulin sensitivity and glucose metabolism |
title_short |
Neuronal control of peripheral insulin sensitivity and glucose metabolism |
title_full |
Neuronal control of peripheral insulin sensitivity and glucose metabolism |
title_fullStr |
Neuronal control of peripheral insulin sensitivity and glucose metabolism |
title_full_unstemmed |
Neuronal control of peripheral insulin sensitivity and glucose metabolism |
title_sort |
neuronal control of peripheral insulin sensitivity and glucose metabolism |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/62a98d37c005424dbfdf3e77a01d017e |
work_keys_str_mv |
AT johanruud neuronalcontrolofperipheralinsulinsensitivityandglucosemetabolism AT sophiemsteculorum neuronalcontrolofperipheralinsulinsensitivityandglucosemetabolism AT jenscbruning neuronalcontrolofperipheralinsulinsensitivityandglucosemetabolism |
_version_ |
1718390240677199872 |