Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers

Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers

Penetration of the mucus and tumor interstitial matrix is an important consideration for drug delivery devices. Here, the authors report on a study into the optimization of rigidity for the transport of nanoparticles through biological hydrogels using core-shell polymer-lipid nanoparticles.

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Autores principales: Miaorong Yu, Lu Xu, Falin Tian, Qian Su, Nan Zheng, Yiwei Yang, Jiuling Wang, Aohua Wang, Chunliu Zhu, Shiyan Guo, XinXin Zhang, Yong Gan, Xinghua Shi, Huajian Gao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/62b09f2339fb4640a540c588e511272e
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spelling oai:doaj.org-article:62b09f2339fb4640a540c588e511272e2021-12-02T15:34:00ZRapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers10.1038/s41467-018-05061-32041-1723https://doaj.org/article/62b09f2339fb4640a540c588e511272e2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05061-3https://doaj.org/toc/2041-1723Penetration of the mucus and tumor interstitial matrix is an important consideration for drug delivery devices. Here, the authors report on a study into the optimization of rigidity for the transport of nanoparticles through biological hydrogels using core-shell polymer-lipid nanoparticles.Miaorong YuLu XuFalin TianQian SuNan ZhengYiwei YangJiuling WangAohua WangChunliu ZhuShiyan GuoXinXin ZhangYong GanXinghua ShiHuajian GaoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Miaorong Yu
Lu Xu
Falin Tian
Qian Su
Nan Zheng
Yiwei Yang
Jiuling Wang
Aohua Wang
Chunliu Zhu
Shiyan Guo
XinXin Zhang
Yong Gan
Xinghua Shi
Huajian Gao
Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers
description Penetration of the mucus and tumor interstitial matrix is an important consideration for drug delivery devices. Here, the authors report on a study into the optimization of rigidity for the transport of nanoparticles through biological hydrogels using core-shell polymer-lipid nanoparticles.
format article
author Miaorong Yu
Lu Xu
Falin Tian
Qian Su
Nan Zheng
Yiwei Yang
Jiuling Wang
Aohua Wang
Chunliu Zhu
Shiyan Guo
XinXin Zhang
Yong Gan
Xinghua Shi
Huajian Gao
author_facet Miaorong Yu
Lu Xu
Falin Tian
Qian Su
Nan Zheng
Yiwei Yang
Jiuling Wang
Aohua Wang
Chunliu Zhu
Shiyan Guo
XinXin Zhang
Yong Gan
Xinghua Shi
Huajian Gao
author_sort Miaorong Yu
title Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers
title_short Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers
title_full Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers
title_fullStr Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers
title_full_unstemmed Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers
title_sort rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/62b09f2339fb4640a540c588e511272e
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