A comparative study on echocardiographic evaluation of left ventricular mass and function in normotensive diabetic and non-diabetic patient

Background: Cardiovascular complications account for the highest mortality in diabetic patients, mainly due to coronary artery disease and congestive heart failure. Left ventricular hypertrophy (LVH) is an ominous prognostic sign and an independent risk factor for cardiac events which is frequently...

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Autores principales:	Tanmay Mukhopadhyay, Pankaj Sarkar, Somnath Naskar, Uttam Biswas, SK Saidul Islam
Formato:	article
Lenguaje:	EN
Publicado:	Manipal College of Medical Sciences, Pokhara 2021
Materias:	diabetes mellitus left ventricular dysfunction left ventricular hypertrophy left ventricular mass index normotensive Medicine R
Acceso en línea:	https://doi.org/10.3126/ajms.v12i12.40013 https://doaj.org/article/62b438710fcd43f187b92a3cda673282
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spelling	oai:doaj.org-article:62b438710fcd43f187b92a3cda6732822021-12-01T13:27:43ZA comparative study on echocardiographic evaluation of left ventricular mass and function in normotensive diabetic and non-diabetic patienthttps://doi.org/10.3126/ajms.v12i12.400132467-91002091-0576https://doaj.org/article/62b438710fcd43f187b92a3cda6732822021-12-01T00:00:00Zhttps://www.nepjol.info/index.php/AJMS/article/view/40013https://doaj.org/toc/2467-9100https://doaj.org/toc/2091-0576Background: Cardiovascular complications account for the highest mortality in diabetic patients, mainly due to coronary artery disease and congestive heart failure. Left ventricular hypertrophy (LVH) is an ominous prognostic sign and an independent risk factor for cardiac events which is frequently present in patients living with diabetes. Aims and Objectives: The aim of the study was to evaluate the LV mass and function in normotensive diabetes patients without antihypertensive medication. Materials and Methods: 100 normotensive diabetic patients were in study group and 100 control patients were studied. Hypertension and other known causes of LVH were excluded from the study. Data were analyzed using proper statistical method. Results: Left ventricular mass index (LVMI) is significantly higher in diabetic patients as compared to control population (P<0.001). It was also observed that the means of the left ventricular posterior wall thickness, interventricular septal thickness, and the left ventricular internal diameter during diastole (in all cases P<0.001) were statistically significantly high in diabetic patients in comparison to healthy control subjects. We have found that a significant systolic dysfunction in diabetic group and diastolic dysfunction also very common in diabetic group than the control group. The LVMI also increased in patients who have longer duration of diabetes and poor glycemic control. Conclusion: LVM is significantly higher in patients of type 2 diabetic without having hypertension, albuminuria, and apparent ischemic heart disease as compared to healthy controls. LVM in diabetic patients increases with duration of diabetes and is positively correlated with HbA1c and blood sugar level.Tanmay Mukhopadhyay Pankaj Sarkar Somnath Naskar Uttam Biswas SK Saidul Islam Manipal College of Medical Sciences, Pokharaarticlediabetes mellitusleft ventricular dysfunctionleft ventricular hypertrophyleft ventricular mass indexnormotensiveMedicineRENAsian Journal of Medical Sciences, Vol 12, Iss 12, Pp 96-102 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	diabetes mellitus left ventricular dysfunction left ventricular hypertrophy left ventricular mass index normotensive Medicine R
spellingShingle	diabetes mellitus left ventricular dysfunction left ventricular hypertrophy left ventricular mass index normotensive Medicine R Tanmay Mukhopadhyay Pankaj Sarkar Somnath Naskar Uttam Biswas SK Saidul Islam A comparative study on echocardiographic evaluation of left ventricular mass and function in normotensive diabetic and non-diabetic patient
description	Background: Cardiovascular complications account for the highest mortality in diabetic patients, mainly due to coronary artery disease and congestive heart failure. Left ventricular hypertrophy (LVH) is an ominous prognostic sign and an independent risk factor for cardiac events which is frequently present in patients living with diabetes. Aims and Objectives: The aim of the study was to evaluate the LV mass and function in normotensive diabetes patients without antihypertensive medication. Materials and Methods: 100 normotensive diabetic patients were in study group and 100 control patients were studied. Hypertension and other known causes of LVH were excluded from the study. Data were analyzed using proper statistical method. Results: Left ventricular mass index (LVMI) is significantly higher in diabetic patients as compared to control population (P<0.001). It was also observed that the means of the left ventricular posterior wall thickness, interventricular septal thickness, and the left ventricular internal diameter during diastole (in all cases P<0.001) were statistically significantly high in diabetic patients in comparison to healthy control subjects. We have found that a significant systolic dysfunction in diabetic group and diastolic dysfunction also very common in diabetic group than the control group. The LVMI also increased in patients who have longer duration of diabetes and poor glycemic control. Conclusion: LVM is significantly higher in patients of type 2 diabetic without having hypertension, albuminuria, and apparent ischemic heart disease as compared to healthy controls. LVM in diabetic patients increases with duration of diabetes and is positively correlated with HbA1c and blood sugar level.
format	article
author	Tanmay Mukhopadhyay Pankaj Sarkar Somnath Naskar Uttam Biswas SK Saidul Islam
author_facet	Tanmay Mukhopadhyay Pankaj Sarkar Somnath Naskar Uttam Biswas SK Saidul Islam
author_sort	Tanmay Mukhopadhyay
title	A comparative study on echocardiographic evaluation of left ventricular mass and function in normotensive diabetic and non-diabetic patient
title_short	A comparative study on echocardiographic evaluation of left ventricular mass and function in normotensive diabetic and non-diabetic patient
title_full	A comparative study on echocardiographic evaluation of left ventricular mass and function in normotensive diabetic and non-diabetic patient
title_fullStr	A comparative study on echocardiographic evaluation of left ventricular mass and function in normotensive diabetic and non-diabetic patient
title_full_unstemmed	A comparative study on echocardiographic evaluation of left ventricular mass and function in normotensive diabetic and non-diabetic patient
title_sort	comparative study on echocardiographic evaluation of left ventricular mass and function in normotensive diabetic and non-diabetic patient
publisher	Manipal College of Medical Sciences, Pokhara
publishDate	2021
url	https://doi.org/10.3126/ajms.v12i12.40013 https://doaj.org/article/62b438710fcd43f187b92a3cda673282
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A comparative study on echocardiographic evaluation of left ventricular mass and function in normotensive diabetic and non-diabetic patient

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