Genotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface

Hepatitis E virus (HEV) infection can result in severe placental disease, but mechanisms underlying pathogenicity are poorly understood. Here, the authors develop an ex vivo model for HEV infection at the maternal-fetal interface and compare pathogenicity of different HEV genotypes.

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Autores principales:	Jordi Gouilly, Qian Chen, Johan Siewiera, Géraldine Cartron, Claude Levy, Martine Dubois, Reem Al-Daccak, Jacques Izopet, Nabila Jabrane-Ferrat, Hicham El Costa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/62b57a30f9f24ff88521f9f37789bf79
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spelling	oai:doaj.org-article:62b57a30f9f24ff88521f9f37789bf792021-12-02T15:33:58ZGenotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface10.1038/s41467-018-07200-22041-1723https://doaj.org/article/62b57a30f9f24ff88521f9f37789bf792018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07200-2https://doaj.org/toc/2041-1723Hepatitis E virus (HEV) infection can result in severe placental disease, but mechanisms underlying pathogenicity are poorly understood. Here, the authors develop an ex vivo model for HEV infection at the maternal-fetal interface and compare pathogenicity of different HEV genotypes.Jordi GouillyQian ChenJohan SiewieraGéraldine CartronClaude LevyMartine DuboisReem Al-DaccakJacques IzopetNabila Jabrane-FerratHicham El CostaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jordi Gouilly Qian Chen Johan Siewiera Géraldine Cartron Claude Levy Martine Dubois Reem Al-Daccak Jacques Izopet Nabila Jabrane-Ferrat Hicham El Costa Genotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface
description	Hepatitis E virus (HEV) infection can result in severe placental disease, but mechanisms underlying pathogenicity are poorly understood. Here, the authors develop an ex vivo model for HEV infection at the maternal-fetal interface and compare pathogenicity of different HEV genotypes.
format	article
author	Jordi Gouilly Qian Chen Johan Siewiera Géraldine Cartron Claude Levy Martine Dubois Reem Al-Daccak Jacques Izopet Nabila Jabrane-Ferrat Hicham El Costa
author_facet	Jordi Gouilly Qian Chen Johan Siewiera Géraldine Cartron Claude Levy Martine Dubois Reem Al-Daccak Jacques Izopet Nabila Jabrane-Ferrat Hicham El Costa
author_sort	Jordi Gouilly
title	Genotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface
title_short	Genotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface
title_full	Genotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface
title_fullStr	Genotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface
title_full_unstemmed	Genotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface
title_sort	genotype specific pathogenicity of hepatitis e virus at the human maternal-fetal interface
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/62b57a30f9f24ff88521f9f37789bf79
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Genotype specific pathogenicity of hepatitis E virus at the human maternal-fetal interface

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