JAK2 V617F genotype is a strong determinant of blast transformation in primary myelofibrosis.

JAK2 V617F genotype is a strong determinant of blast transformation in primary myelofibrosis.

<h4>Purpose</h4>The influence of JAK2 V617F mutation on blast transformation (BT) and overall survival (OS) in primary myelofibrosis (PMF) is controversial. In a large cohort of patients we applied competing risks analysis for studying the influence of JAK2V617F mutation on BT in PMF.<...

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Autores principales: Giovanni Barosi, Valentina Poletto, Margherita Massa, Rita Campanelli, Laura Villani, Elisa Bonetti, Gianluca Viarengo, Paolo Catarsi, Catherine Klersy, Vittorio Rosti
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/62b9e45bc5d548c6a06efc5fec3c0200
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