PRLR-AluI Gene Polymorphism And Litter Size Traits In Highly Prolific Line Of Topigs 20 Sows

The objective of the present study was to identify the Prolactin Receptor (PRLR) gene polymorphism related to litter size traits. The study included 101 Topigs 20 line of sows with 426 litters. The traits studied were: Total Number of Born (TNB), Number of Born Alive (NBA), Number of Still Born (NSB...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Menčik Sven, Vuković Vlado, Modrić Mario, Špehar Marija, Ostović Mario, Sušić Velimir, Štoković Igor, Samardžija Marko, Ekert Kabalin Anamaria
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2015
Materias:	prolactin receptor gene litter size pigs topigs 20 Veterinary medicine SF600-1100
Acceso en línea:	https://doaj.org/article/62d01c26ae264cf98e867b5db766b09f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:62d01c26ae264cf98e867b5db766b09f
record_format	dspace
spelling	oai:doaj.org-article:62d01c26ae264cf98e867b5db766b09f2021-11-17T21:27:50ZPRLR-AluI Gene Polymorphism And Litter Size Traits In Highly Prolific Line Of Topigs 20 Sows1820-744810.1515/acve-2015-0039https://doaj.org/article/62d01c26ae264cf98e867b5db766b09f2015-12-01T00:00:00Zhttps://doi.org/10.1515/acve-2015-0039https://doaj.org/toc/1820-7448The objective of the present study was to identify the Prolactin Receptor (PRLR) gene polymorphism related to litter size traits. The study included 101 Topigs 20 line of sows with 426 litters. The traits studied were: Total Number of Born (TNB), Number of Born Alive (NBA), Number of Still Born (NSB), and Number of MUMmified (NMUM) piglets. Polymorphism was identified with the polymerase chain reaction-restriction fragment length polymorphism method. Allelic and genotype frequencies and deviation from Hardy-Weinberg equilibrium were verified with the chi-square test. Analysis of litter size traits was performed using the General Linear Model, which included the potential environmental effects. Additive and dominant allele variances were observed by the regression procedure. In the studied population of sows, the frequency of heterozygotes (0.5149) for PRLR gene exceeded the total number of AA (0.0198) and BB (0.4653) homozygotes, which resulted in a high proportion of B allele (0.7228). The results for PRLR showed statistically significant (P<0.05) differences in first parity sows between BB and AB genotypes for TNB and NBA. Significant differences (P<0.05) were recorded in third parity sows between BB and AB genotypes for NBA, and in AA genotype versus AB and BB genotypes for NMUM. The fourth and subsequent parity sows of AA genotype had a significantly higher (P<0.05) rate of NBA as compared with those of AB and BB genotypes. In all parities analysed, the difference between the BB and AB genotypes for NBA was statistically significant (P<0.05). Interpretation of the results at the levels of phenotypes and either additive or dominant variance was quite difficult due to the small number of AA homozygous sows. The calculation model yielded a significant effect (P<0.05) as well as tendency (P<0.1) for the mentioned effects except for age at first farrowing.Menčik SvenVuković VladoModrić MarioŠpehar MarijaOstović MarioSušić VelimirŠtoković IgorSamardžija MarkoEkert Kabalin AnamariaSciendoarticleprolactin receptor genelitter sizepigstopigs 20Veterinary medicineSF600-1100ENActa Veterinaria, Vol 65, Iss 4, Pp 463-476 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	prolactin receptor gene litter size pigs topigs 20 Veterinary medicine SF600-1100
spellingShingle	prolactin receptor gene litter size pigs topigs 20 Veterinary medicine SF600-1100 Menčik Sven Vuković Vlado Modrić Mario Špehar Marija Ostović Mario Sušić Velimir Štoković Igor Samardžija Marko Ekert Kabalin Anamaria PRLR-AluI Gene Polymorphism And Litter Size Traits In Highly Prolific Line Of Topigs 20 Sows
description	The objective of the present study was to identify the Prolactin Receptor (PRLR) gene polymorphism related to litter size traits. The study included 101 Topigs 20 line of sows with 426 litters. The traits studied were: Total Number of Born (TNB), Number of Born Alive (NBA), Number of Still Born (NSB), and Number of MUMmified (NMUM) piglets. Polymorphism was identified with the polymerase chain reaction-restriction fragment length polymorphism method. Allelic and genotype frequencies and deviation from Hardy-Weinberg equilibrium were verified with the chi-square test. Analysis of litter size traits was performed using the General Linear Model, which included the potential environmental effects. Additive and dominant allele variances were observed by the regression procedure. In the studied population of sows, the frequency of heterozygotes (0.5149) for PRLR gene exceeded the total number of AA (0.0198) and BB (0.4653) homozygotes, which resulted in a high proportion of B allele (0.7228). The results for PRLR showed statistically significant (P<0.05) differences in first parity sows between BB and AB genotypes for TNB and NBA. Significant differences (P<0.05) were recorded in third parity sows between BB and AB genotypes for NBA, and in AA genotype versus AB and BB genotypes for NMUM. The fourth and subsequent parity sows of AA genotype had a significantly higher (P<0.05) rate of NBA as compared with those of AB and BB genotypes. In all parities analysed, the difference between the BB and AB genotypes for NBA was statistically significant (P<0.05). Interpretation of the results at the levels of phenotypes and either additive or dominant variance was quite difficult due to the small number of AA homozygous sows. The calculation model yielded a significant effect (P<0.05) as well as tendency (P<0.1) for the mentioned effects except for age at first farrowing.
format	article
author	Menčik Sven Vuković Vlado Modrić Mario Špehar Marija Ostović Mario Sušić Velimir Štoković Igor Samardžija Marko Ekert Kabalin Anamaria
author_facet	Menčik Sven Vuković Vlado Modrić Mario Špehar Marija Ostović Mario Sušić Velimir Štoković Igor Samardžija Marko Ekert Kabalin Anamaria
author_sort	Menčik Sven
title	PRLR-AluI Gene Polymorphism And Litter Size Traits In Highly Prolific Line Of Topigs 20 Sows
title_short	PRLR-AluI Gene Polymorphism And Litter Size Traits In Highly Prolific Line Of Topigs 20 Sows
title_full	PRLR-AluI Gene Polymorphism And Litter Size Traits In Highly Prolific Line Of Topigs 20 Sows
title_fullStr	PRLR-AluI Gene Polymorphism And Litter Size Traits In Highly Prolific Line Of Topigs 20 Sows
title_full_unstemmed	PRLR-AluI Gene Polymorphism And Litter Size Traits In Highly Prolific Line Of Topigs 20 Sows
title_sort	prlr-alui gene polymorphism and litter size traits in highly prolific line of topigs 20 sows
publisher	Sciendo
publishDate	2015
url	https://doaj.org/article/62d01c26ae264cf98e867b5db766b09f
work_keys_str_mv	AT menciksven prlraluigenepolymorphismandlittersizetraitsinhighlyprolificlineoftopigs20sows AT vukovicvlado prlraluigenepolymorphismandlittersizetraitsinhighlyprolificlineoftopigs20sows AT modricmario prlraluigenepolymorphismandlittersizetraitsinhighlyprolificlineoftopigs20sows AT speharmarija prlraluigenepolymorphismandlittersizetraitsinhighlyprolificlineoftopigs20sows AT ostovicmario prlraluigenepolymorphismandlittersizetraitsinhighlyprolificlineoftopigs20sows AT susicvelimir prlraluigenepolymorphismandlittersizetraitsinhighlyprolificlineoftopigs20sows AT stokovicigor prlraluigenepolymorphismandlittersizetraitsinhighlyprolificlineoftopigs20sows AT samardzijamarko prlraluigenepolymorphismandlittersizetraitsinhighlyprolificlineoftopigs20sows AT ekertkabalinanamaria prlraluigenepolymorphismandlittersizetraitsinhighlyprolificlineoftopigs20sows
_version_	1718425358707982336

PRLR-AluI Gene Polymorphism And Litter Size Traits In Highly Prolific Line Of Topigs 20 Sows

Ejemplares similares