(Pro)renin receptor triggers distinct angiotensin II-independent extracellular matrix remodeling and deterioration of cardiac function.

<h4>Background</h4>Activation of the renin-angiotensin-system (RAS) plays a key pathophysiological role in heart failure in patients with hypertension and myocardial infarction. However, the function of (pro)renin receptor ((P)RR) is not yet solved. We determined here the direct function...

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Autores principales: Anne-Mari Moilanen, Jaana Rysä, Raisa Serpi, Erja Mustonen, Zoltán Szabò, Jani Aro, Juha Näpänkangas, Olli Tenhunen, Meeri Sutinen, Tuula Salo, Heikki Ruskoaho
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/62daa18b1bda4fc68426b9d44b6eae67
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