Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection
Spores produced by Clostridioides difficile during infection are important for the recurrence of the disease. Here, Castro-Córdova et al. show that the spores gain entry into the intestinal mucosa via pathways dependent on host fibronectin and vitronectin, and spore entry inhibition leads to reduced...
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Autores principales: | Pablo Castro-Córdova, Paola Mora-Uribe, Rodrigo Reyes-Ramírez, Glenda Cofré-Araneda, Josué Orozco-Aguilar, Christian Brito-Silva, María José Mendoza-León, Sarah A. Kuehne, Nigel P. Minton, Marjorie Pizarro-Guajardo, Daniel Paredes-Sabja |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/62ebad3827eb4925817d4a2de6d0326f |
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