Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer
Genetic variants associated with susceptibility to pancreatic cancer have been identified using genome wide association studies (GWAS). Here, the authors combine data from over 9000 patients and perform a meta-analysis to identify five novel loci linked to pancreatic cancer.
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Nature Portfolio
2018
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oai:doaj.org-article:62f48b33d3e24b21a7c8f4e240a960a12021-12-02T16:49:21ZGenome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer10.1038/s41467-018-02942-52041-1723https://doaj.org/article/62f48b33d3e24b21a7c8f4e240a960a12018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02942-5https://doaj.org/toc/2041-1723Genetic variants associated with susceptibility to pancreatic cancer have been identified using genome wide association studies (GWAS). Here, the authors combine data from over 9000 patients and perform a meta-analysis to identify five novel loci linked to pancreatic cancer.Alison P. KleinBrian M. WolpinHarvey A. RischRachael Z. Stolzenberg-SolomonEvelina MocciMingfeng ZhangFederico CanzianErica J. ChildsJason W. HoskinsAshley JermusykJun ZhongFei ChenDemetrius AlbanesGabriella AndreottiAlan A. ArslanAna BabicWilliam R. BamletLaura Beane-FreemanSonja I. BerndtAmanda BlackfordMichael BorgesAyelet BorgidaPaige M. BracciLauren BraisPaul BrennanHermann BrennerBas Bueno-de-MesquitaJulie BuringDaniele CampaGabriele CapursoGiulia Martina CavestroKari G. ChaffeeCharles C. ChungSean ClearyMichelle CotterchioFrederike DijkEric J. DuellLenka ForetovaCharles FuchsNiccola FunelSteven GallingerJ. Michael M. GazianoMaria GazouliGraham G. GilesEdward GiovannucciMichael GogginsGary E. GoodmanPhyllis J. GoodmanThilo HackertChristopher HaimanPatricia HartgeManal HasanPeter HegyiKathy J. HelzlsouerJoseph HermanIvana HolcatovaElizabeth A. HollyRobert HooverRayjean J. HungEric J. JacobsKrzysztof JamroziakVladimir JanoutRudolf KaaksKay-Tee KhawEric A. KleinManolis KogevinasCharles KooperbergMatthew H. KulkeJuozas KupcinskasRobert J. KurtzDaniel LaheruStefano LandiRita T. LawlorI.-Min LeeLoic LeMarchandLingeng LuNúria MalatsAndrea MambriniSatu MannistoRoger L. MilneBeatrice Mohelníková-DuchoňováRachel E. NealeJohn P. NeoptolemosAnn L. ObergSara H. OlsonIrene OrlowClaudio PasqualiAlpa V. PatelUlrike PetersRaffaele PezzilliMiquel PortaFrancisco X. RealNathaniel RothmanGhislaine SceloHoward D. SessoGianluca SeveriXiao-Ou ShuDebra SilvermanJill P. SmithPavel SoucekMalin SundRenata Talar-WojnarowskaFrancesca TavanoMark D. ThornquistGeoffrey S. TobiasStephen K. Van Den EedenYogesh VashistKala VisvanathanPavel VodickaJean Wactawski-WendeZhaoming WangNicolas WentzensenEmily WhiteHerbert YuKai YuAnne Zeleniuch-JacquotteWei ZhengPeter KraftDonghui LiStephen ChanockOfure ObazeeGloria M. PetersenLaufey T. AmundadottirNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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DOAJ |
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EN |
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Science Q |
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Science Q Alison P. Klein Brian M. Wolpin Harvey A. Risch Rachael Z. Stolzenberg-Solomon Evelina Mocci Mingfeng Zhang Federico Canzian Erica J. Childs Jason W. Hoskins Ashley Jermusyk Jun Zhong Fei Chen Demetrius Albanes Gabriella Andreotti Alan A. Arslan Ana Babic William R. Bamlet Laura Beane-Freeman Sonja I. Berndt Amanda Blackford Michael Borges Ayelet Borgida Paige M. Bracci Lauren Brais Paul Brennan Hermann Brenner Bas Bueno-de-Mesquita Julie Buring Daniele Campa Gabriele Capurso Giulia Martina Cavestro Kari G. Chaffee Charles C. Chung Sean Cleary Michelle Cotterchio Frederike Dijk Eric J. Duell Lenka Foretova Charles Fuchs Niccola Funel Steven Gallinger J. Michael M. Gaziano Maria Gazouli Graham G. Giles Edward Giovannucci Michael Goggins Gary E. Goodman Phyllis J. Goodman Thilo Hackert Christopher Haiman Patricia Hartge Manal Hasan Peter Hegyi Kathy J. Helzlsouer Joseph Herman Ivana Holcatova Elizabeth A. Holly Robert Hoover Rayjean J. Hung Eric J. Jacobs Krzysztof Jamroziak Vladimir Janout Rudolf Kaaks Kay-Tee Khaw Eric A. Klein Manolis Kogevinas Charles Kooperberg Matthew H. Kulke Juozas Kupcinskas Robert J. Kurtz Daniel Laheru Stefano Landi Rita T. Lawlor I.-Min Lee Loic LeMarchand Lingeng Lu Núria Malats Andrea Mambrini Satu Mannisto Roger L. Milne Beatrice Mohelníková-Duchoňová Rachel E. Neale John P. Neoptolemos Ann L. Oberg Sara H. Olson Irene Orlow Claudio Pasquali Alpa V. Patel Ulrike Peters Raffaele Pezzilli Miquel Porta Francisco X. Real Nathaniel Rothman Ghislaine Scelo Howard D. Sesso Gianluca Severi Xiao-Ou Shu Debra Silverman Jill P. Smith Pavel Soucek Malin Sund Renata Talar-Wojnarowska Francesca Tavano Mark D. Thornquist Geoffrey S. Tobias Stephen K. Van Den Eeden Yogesh Vashist Kala Visvanathan Pavel Vodicka Jean Wactawski-Wende Zhaoming Wang Nicolas Wentzensen Emily White Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Wei Zheng Peter Kraft Donghui Li Stephen Chanock Ofure Obazee Gloria M. Petersen Laufey T. Amundadottir Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer |
| description |
Genetic variants associated with susceptibility to pancreatic cancer have been identified using genome wide association studies (GWAS). Here, the authors combine data from over 9000 patients and perform a meta-analysis to identify five novel loci linked to pancreatic cancer. |
| format |
article |
| author |
Alison P. Klein Brian M. Wolpin Harvey A. Risch Rachael Z. Stolzenberg-Solomon Evelina Mocci Mingfeng Zhang Federico Canzian Erica J. Childs Jason W. Hoskins Ashley Jermusyk Jun Zhong Fei Chen Demetrius Albanes Gabriella Andreotti Alan A. Arslan Ana Babic William R. Bamlet Laura Beane-Freeman Sonja I. Berndt Amanda Blackford Michael Borges Ayelet Borgida Paige M. Bracci Lauren Brais Paul Brennan Hermann Brenner Bas Bueno-de-Mesquita Julie Buring Daniele Campa Gabriele Capurso Giulia Martina Cavestro Kari G. Chaffee Charles C. Chung Sean Cleary Michelle Cotterchio Frederike Dijk Eric J. Duell Lenka Foretova Charles Fuchs Niccola Funel Steven Gallinger J. Michael M. Gaziano Maria Gazouli Graham G. Giles Edward Giovannucci Michael Goggins Gary E. Goodman Phyllis J. Goodman Thilo Hackert Christopher Haiman Patricia Hartge Manal Hasan Peter Hegyi Kathy J. Helzlsouer Joseph Herman Ivana Holcatova Elizabeth A. Holly Robert Hoover Rayjean J. Hung Eric J. Jacobs Krzysztof Jamroziak Vladimir Janout Rudolf Kaaks Kay-Tee Khaw Eric A. Klein Manolis Kogevinas Charles Kooperberg Matthew H. Kulke Juozas Kupcinskas Robert J. Kurtz Daniel Laheru Stefano Landi Rita T. Lawlor I.-Min Lee Loic LeMarchand Lingeng Lu Núria Malats Andrea Mambrini Satu Mannisto Roger L. Milne Beatrice Mohelníková-Duchoňová Rachel E. Neale John P. Neoptolemos Ann L. Oberg Sara H. Olson Irene Orlow Claudio Pasquali Alpa V. Patel Ulrike Peters Raffaele Pezzilli Miquel Porta Francisco X. Real Nathaniel Rothman Ghislaine Scelo Howard D. Sesso Gianluca Severi Xiao-Ou Shu Debra Silverman Jill P. Smith Pavel Soucek Malin Sund Renata Talar-Wojnarowska Francesca Tavano Mark D. Thornquist Geoffrey S. Tobias Stephen K. Van Den Eeden Yogesh Vashist Kala Visvanathan Pavel Vodicka Jean Wactawski-Wende Zhaoming Wang Nicolas Wentzensen Emily White Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Wei Zheng Peter Kraft Donghui Li Stephen Chanock Ofure Obazee Gloria M. Petersen Laufey T. Amundadottir |
| author_facet |
Alison P. Klein Brian M. Wolpin Harvey A. Risch Rachael Z. Stolzenberg-Solomon Evelina Mocci Mingfeng Zhang Federico Canzian Erica J. Childs Jason W. Hoskins Ashley Jermusyk Jun Zhong Fei Chen Demetrius Albanes Gabriella Andreotti Alan A. Arslan Ana Babic William R. Bamlet Laura Beane-Freeman Sonja I. Berndt Amanda Blackford Michael Borges Ayelet Borgida Paige M. Bracci Lauren Brais Paul Brennan Hermann Brenner Bas Bueno-de-Mesquita Julie Buring Daniele Campa Gabriele Capurso Giulia Martina Cavestro Kari G. Chaffee Charles C. Chung Sean Cleary Michelle Cotterchio Frederike Dijk Eric J. Duell Lenka Foretova Charles Fuchs Niccola Funel Steven Gallinger J. Michael M. Gaziano Maria Gazouli Graham G. Giles Edward Giovannucci Michael Goggins Gary E. Goodman Phyllis J. Goodman Thilo Hackert Christopher Haiman Patricia Hartge Manal Hasan Peter Hegyi Kathy J. Helzlsouer Joseph Herman Ivana Holcatova Elizabeth A. Holly Robert Hoover Rayjean J. Hung Eric J. Jacobs Krzysztof Jamroziak Vladimir Janout Rudolf Kaaks Kay-Tee Khaw Eric A. Klein Manolis Kogevinas Charles Kooperberg Matthew H. Kulke Juozas Kupcinskas Robert J. Kurtz Daniel Laheru Stefano Landi Rita T. Lawlor I.-Min Lee Loic LeMarchand Lingeng Lu Núria Malats Andrea Mambrini Satu Mannisto Roger L. Milne Beatrice Mohelníková-Duchoňová Rachel E. Neale John P. Neoptolemos Ann L. Oberg Sara H. Olson Irene Orlow Claudio Pasquali Alpa V. Patel Ulrike Peters Raffaele Pezzilli Miquel Porta Francisco X. Real Nathaniel Rothman Ghislaine Scelo Howard D. Sesso Gianluca Severi Xiao-Ou Shu Debra Silverman Jill P. Smith Pavel Soucek Malin Sund Renata Talar-Wojnarowska Francesca Tavano Mark D. Thornquist Geoffrey S. Tobias Stephen K. Van Den Eeden Yogesh Vashist Kala Visvanathan Pavel Vodicka Jean Wactawski-Wende Zhaoming Wang Nicolas Wentzensen Emily White Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Wei Zheng Peter Kraft Donghui Li Stephen Chanock Ofure Obazee Gloria M. Petersen Laufey T. Amundadottir |
| author_sort |
Alison P. Klein |
| title |
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer |
| title_short |
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer |
| title_full |
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer |
| title_fullStr |
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer |
| title_full_unstemmed |
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer |
| title_sort |
genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/62f48b33d3e24b21a7c8f4e240a960a1 |
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