Brachial-Ankle Pulse Wave Velocity is Associated with the Risk of New Carotid Plaque Formation: Data from a Chinese Community-based Cohort

Abstract Artery stiffness is an independent marker for atherosclerotic cardiovascular diseases. However, whether the brachial-ankle pulse wave velocity (ba-PWV) is related to new carotid plaque formation is unresolved. This study aimed to investigate the association between baseline ba-PWV and new c...

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Autores principales:	Yao Yang, Fangfang Fan, Minghao Kou, Ying Yang, Guanliang Cheng, Jia Jia, Lan Gao, Zechen Zhou, Dafang Chen, Yan Zhang, Yong Huo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/62f863657aef49c2927cd61d87b503ed
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spelling	oai:doaj.org-article:62f863657aef49c2927cd61d87b503ed2021-12-02T11:40:35ZBrachial-Ankle Pulse Wave Velocity is Associated with the Risk of New Carotid Plaque Formation: Data from a Chinese Community-based Cohort10.1038/s41598-018-25579-22045-2322https://doaj.org/article/62f863657aef49c2927cd61d87b503ed2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-25579-2https://doaj.org/toc/2045-2322Abstract Artery stiffness is an independent marker for atherosclerotic cardiovascular diseases. However, whether the brachial-ankle pulse wave velocity (ba-PWV) is related to new carotid plaque formation is unresolved. This study aimed to investigate the association between baseline ba-PWV and new carotid plaque formation in a Chinese community-based population without carotid plaques at baseline. This study population consisted of a total of 738 participants from an atherosclerosis cohort in Beijing, China. After a mean 2.3-year follow-up, the incidence of carotid plaques were 21.2% and 36.5% in the groups with ba-PWV < 1,400 cm/s and ≥1,400 cm/s, respectively. Compared with baseline ba-PWV < 1,400 cm/s group, ba-PWV ≥ 1,400 cm/s group was significantly associated with the incidence of new carotid plaque formation (odds ratio [OR] = 2.14, 95% CI: 1.50–3.03, P < 0.01), even after adjusting for common risk factors (OR = 1.52, 95% CI: 1.02–2.25, P = 0.04). Furthermore, there was a strong relationship between baseline ba-PWV and carotid plaque formation in subjects with ba-PWV < 1,400 cm/s, but no such relationship was found in subjects with baseline ba-PWV ≥ 1,400 cm/s. In conclusion, this study suggests that baseline ba-PWV is independently associated with the risk of carotid plaque formation in a Chinese community-based population.Yao YangFangfang FanMinghao KouYing YangGuanliang ChengJia JiaLan GaoZechen ZhouDafang ChenYan ZhangYong HuoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yao Yang Fangfang Fan Minghao Kou Ying Yang Guanliang Cheng Jia Jia Lan Gao Zechen Zhou Dafang Chen Yan Zhang Yong Huo Brachial-Ankle Pulse Wave Velocity is Associated with the Risk of New Carotid Plaque Formation: Data from a Chinese Community-based Cohort
description	Abstract Artery stiffness is an independent marker for atherosclerotic cardiovascular diseases. However, whether the brachial-ankle pulse wave velocity (ba-PWV) is related to new carotid plaque formation is unresolved. This study aimed to investigate the association between baseline ba-PWV and new carotid plaque formation in a Chinese community-based population without carotid plaques at baseline. This study population consisted of a total of 738 participants from an atherosclerosis cohort in Beijing, China. After a mean 2.3-year follow-up, the incidence of carotid plaques were 21.2% and 36.5% in the groups with ba-PWV < 1,400 cm/s and ≥1,400 cm/s, respectively. Compared with baseline ba-PWV < 1,400 cm/s group, ba-PWV ≥ 1,400 cm/s group was significantly associated with the incidence of new carotid plaque formation (odds ratio [OR] = 2.14, 95% CI: 1.50–3.03, P < 0.01), even after adjusting for common risk factors (OR = 1.52, 95% CI: 1.02–2.25, P = 0.04). Furthermore, there was a strong relationship between baseline ba-PWV and carotid plaque formation in subjects with ba-PWV < 1,400 cm/s, but no such relationship was found in subjects with baseline ba-PWV ≥ 1,400 cm/s. In conclusion, this study suggests that baseline ba-PWV is independently associated with the risk of carotid plaque formation in a Chinese community-based population.
format	article
author	Yao Yang Fangfang Fan Minghao Kou Ying Yang Guanliang Cheng Jia Jia Lan Gao Zechen Zhou Dafang Chen Yan Zhang Yong Huo
author_facet	Yao Yang Fangfang Fan Minghao Kou Ying Yang Guanliang Cheng Jia Jia Lan Gao Zechen Zhou Dafang Chen Yan Zhang Yong Huo
author_sort	Yao Yang
title	Brachial-Ankle Pulse Wave Velocity is Associated with the Risk of New Carotid Plaque Formation: Data from a Chinese Community-based Cohort
title_short	Brachial-Ankle Pulse Wave Velocity is Associated with the Risk of New Carotid Plaque Formation: Data from a Chinese Community-based Cohort
title_full	Brachial-Ankle Pulse Wave Velocity is Associated with the Risk of New Carotid Plaque Formation: Data from a Chinese Community-based Cohort
title_fullStr	Brachial-Ankle Pulse Wave Velocity is Associated with the Risk of New Carotid Plaque Formation: Data from a Chinese Community-based Cohort
title_full_unstemmed	Brachial-Ankle Pulse Wave Velocity is Associated with the Risk of New Carotid Plaque Formation: Data from a Chinese Community-based Cohort
title_sort	brachial-ankle pulse wave velocity is associated with the risk of new carotid plaque formation: data from a chinese community-based cohort
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/62f863657aef49c2927cd61d87b503ed
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Brachial-Ankle Pulse Wave Velocity is Associated with the Risk of New Carotid Plaque Formation: Data from a Chinese Community-based Cohort

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