Novel non intrusive continuous use ZeBox technology to trap and kill airborne microbes

Abstract Preventing nosocomial infection is a major unmet need of our times. Existing air decontamination technologies suffer from demerits such as toxicity of exposure, species specificity, noxious gas emission, environment-dependent performance and high power consumption. Here, we present a novel...

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Autores principales:	Kruttika S. Phadke, Deepak G. Madival, Janani Venkataraman, Debosmita Kundu, K. S. Ramanujan, Nisha Holla, Jaywant Arakeri, Gaurav Tomar, Santanu Datta, Arindam Ghatak
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/63023a1df1a2446096527448c3bc9c58
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spelling	oai:doaj.org-article:63023a1df1a2446096527448c3bc9c582021-11-28T12:16:16ZNovel non intrusive continuous use ZeBox technology to trap and kill airborne microbes10.1038/s41598-021-02184-42045-2322https://doaj.org/article/63023a1df1a2446096527448c3bc9c582021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02184-4https://doaj.org/toc/2045-2322Abstract Preventing nosocomial infection is a major unmet need of our times. Existing air decontamination technologies suffer from demerits such as toxicity of exposure, species specificity, noxious gas emission, environment-dependent performance and high power consumption. Here, we present a novel technology called “ZeBox” that transcends the conventional limitations and achieves high microbicidal efficiency. In ZeBox, a non-ionizing electric field extracts naturally charged microbes from flowing air and deposits them on engineered microbicidal surfaces. The surface’s three dimensional topography traps the microbes long enough for them to be inactivated. The electric field and chemical surfaces synergistically achieve rapid inactivation of a broad spectrum of microbes. ZeBox achieved near complete kill of airborne microbes in challenge tests (5–9 log reduction) and $$>90\%$$ > 90 % efficiency in a fully functional stem cell research facility in the presence of humans. Thus, ZeBox fulfills the dire need for a real-time, continuous, safe, trap-and-kill air decontamination technology.Kruttika S. PhadkeDeepak G. MadivalJanani VenkataramanDebosmita KunduK. S. RamanujanNisha HollaJaywant ArakeriGaurav TomarSantanu DattaArindam GhatakNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kruttika S. Phadke Deepak G. Madival Janani Venkataraman Debosmita Kundu K. S. Ramanujan Nisha Holla Jaywant Arakeri Gaurav Tomar Santanu Datta Arindam Ghatak Novel non intrusive continuous use ZeBox technology to trap and kill airborne microbes
description	Abstract Preventing nosocomial infection is a major unmet need of our times. Existing air decontamination technologies suffer from demerits such as toxicity of exposure, species specificity, noxious gas emission, environment-dependent performance and high power consumption. Here, we present a novel technology called “ZeBox” that transcends the conventional limitations and achieves high microbicidal efficiency. In ZeBox, a non-ionizing electric field extracts naturally charged microbes from flowing air and deposits them on engineered microbicidal surfaces. The surface’s three dimensional topography traps the microbes long enough for them to be inactivated. The electric field and chemical surfaces synergistically achieve rapid inactivation of a broad spectrum of microbes. ZeBox achieved near complete kill of airborne microbes in challenge tests (5–9 log reduction) and $$>90\%$$ > 90 % efficiency in a fully functional stem cell research facility in the presence of humans. Thus, ZeBox fulfills the dire need for a real-time, continuous, safe, trap-and-kill air decontamination technology.
format	article
author	Kruttika S. Phadke Deepak G. Madival Janani Venkataraman Debosmita Kundu K. S. Ramanujan Nisha Holla Jaywant Arakeri Gaurav Tomar Santanu Datta Arindam Ghatak
author_facet	Kruttika S. Phadke Deepak G. Madival Janani Venkataraman Debosmita Kundu K. S. Ramanujan Nisha Holla Jaywant Arakeri Gaurav Tomar Santanu Datta Arindam Ghatak
author_sort	Kruttika S. Phadke
title	Novel non intrusive continuous use ZeBox technology to trap and kill airborne microbes
title_short	Novel non intrusive continuous use ZeBox technology to trap and kill airborne microbes
title_full	Novel non intrusive continuous use ZeBox technology to trap and kill airborne microbes
title_fullStr	Novel non intrusive continuous use ZeBox technology to trap and kill airborne microbes
title_full_unstemmed	Novel non intrusive continuous use ZeBox technology to trap and kill airborne microbes
title_sort	novel non intrusive continuous use zebox technology to trap and kill airborne microbes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/63023a1df1a2446096527448c3bc9c58
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Novel non intrusive continuous use ZeBox technology to trap and kill airborne microbes

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