Comparison of penetrating keratoplasty outcomes with or without microwave thermokeratoplasty

Abstract Microwave thermokeratoplasty (MTK) is a surgical procedure for the correction of pathologic corneal steepening. The purpose of this study was to examine the postoperative outcomes of eyes with advanced keratoconus that underwent femtosecond-laser zig-zag penetrating keratoplasty (z-PK) foll...

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Autores principales:	Osamu Hieda, Koichi Wakimasu, Shigeru Kinoshita, Chie Sotozono
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/63086470645348fba9460691b7b7b519
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spelling	oai:doaj.org-article:63086470645348fba9460691b7b7b5192021-12-02T17:05:11ZComparison of penetrating keratoplasty outcomes with or without microwave thermokeratoplasty10.1038/s41598-021-85470-52045-2322https://doaj.org/article/63086470645348fba9460691b7b7b5192021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-85470-5https://doaj.org/toc/2045-2322Abstract Microwave thermokeratoplasty (MTK) is a surgical procedure for the correction of pathologic corneal steepening. The purpose of this study was to examine the postoperative outcomes of eyes with advanced keratoconus that underwent femtosecond-laser zig-zag penetrating keratoplasty (z-PK) following MTK for reshaping of the central cornea. This study involved 32 eyes of 32 consecutive advanced keratoconus patients; i.e., 25 eyes of 25 patients who underwent MTK prior to z-PK (MTK + z-PK group), and 7 eyes of 7 patients who underwent z-PK alone (z-PK group). In all treated eyes, visual acuity (VA) and corneal topography were measured before surgery and at 6-months postoperative. At 6-months postoperative, the mean uncorrected distance VA (logarithm of the minimum angle of resolution) and surface regularity index (SRI) of the MTK + z-PK group was 0.62 ± 0.39 (mean ± standard deviation) and 1.26 ± 0.45, respectively, while that in the z-PK group was 1.02 ± 0.18 and 7.64 ± 3.22, respectively. Both variables were significantly better in the MTK + z-PK group than in the z-PK group (P < 0.05). The findings in this study reveal that MTK prior to z-PKP is effective for improving UDVA and reducing the irregularity of corneal topography in patients with advanced keratoconus.Osamu HiedaKoichi WakimasuShigeru KinoshitaChie SotozonoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Osamu Hieda Koichi Wakimasu Shigeru Kinoshita Chie Sotozono Comparison of penetrating keratoplasty outcomes with or without microwave thermokeratoplasty
description	Abstract Microwave thermokeratoplasty (MTK) is a surgical procedure for the correction of pathologic corneal steepening. The purpose of this study was to examine the postoperative outcomes of eyes with advanced keratoconus that underwent femtosecond-laser zig-zag penetrating keratoplasty (z-PK) following MTK for reshaping of the central cornea. This study involved 32 eyes of 32 consecutive advanced keratoconus patients; i.e., 25 eyes of 25 patients who underwent MTK prior to z-PK (MTK + z-PK group), and 7 eyes of 7 patients who underwent z-PK alone (z-PK group). In all treated eyes, visual acuity (VA) and corneal topography were measured before surgery and at 6-months postoperative. At 6-months postoperative, the mean uncorrected distance VA (logarithm of the minimum angle of resolution) and surface regularity index (SRI) of the MTK + z-PK group was 0.62 ± 0.39 (mean ± standard deviation) and 1.26 ± 0.45, respectively, while that in the z-PK group was 1.02 ± 0.18 and 7.64 ± 3.22, respectively. Both variables were significantly better in the MTK + z-PK group than in the z-PK group (P < 0.05). The findings in this study reveal that MTK prior to z-PKP is effective for improving UDVA and reducing the irregularity of corneal topography in patients with advanced keratoconus.
format	article
author	Osamu Hieda Koichi Wakimasu Shigeru Kinoshita Chie Sotozono
author_facet	Osamu Hieda Koichi Wakimasu Shigeru Kinoshita Chie Sotozono
author_sort	Osamu Hieda
title	Comparison of penetrating keratoplasty outcomes with or without microwave thermokeratoplasty
title_short	Comparison of penetrating keratoplasty outcomes with or without microwave thermokeratoplasty
title_full	Comparison of penetrating keratoplasty outcomes with or without microwave thermokeratoplasty
title_fullStr	Comparison of penetrating keratoplasty outcomes with or without microwave thermokeratoplasty
title_full_unstemmed	Comparison of penetrating keratoplasty outcomes with or without microwave thermokeratoplasty
title_sort	comparison of penetrating keratoplasty outcomes with or without microwave thermokeratoplasty
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/63086470645348fba9460691b7b7b519
work_keys_str_mv	AT osamuhieda comparisonofpenetratingkeratoplastyoutcomeswithorwithoutmicrowavethermokeratoplasty AT koichiwakimasu comparisonofpenetratingkeratoplastyoutcomeswithorwithoutmicrowavethermokeratoplasty AT shigerukinoshita comparisonofpenetratingkeratoplastyoutcomeswithorwithoutmicrowavethermokeratoplasty AT chiesotozono comparisonofpenetratingkeratoplastyoutcomeswithorwithoutmicrowavethermokeratoplasty
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Comparison of penetrating keratoplasty outcomes with or without microwave thermokeratoplasty

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