Exploratory adaptation in large random networks

Recent works suggest that cellular networks may respond to novel challenges on the time-scale of cellular lifetimes through large-scale perturbation of gene expression and convergence to a new state. Here, the authors demonstrate the theoretical feasibility of exploratory adaptation in cellular netw...

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Main Authors:	Hallel I. Schreier, Yoav Soen, Naama Brenner
Format:	article
Language:	EN
Published:	Nature Portfolio 2017
Subjects:	Science Q
Online Access:	https://doaj.org/article/63091e04f7cc4fa1aaff740c34dc4804
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id	oai:doaj.org-article:63091e04f7cc4fa1aaff740c34dc4804
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spelling	oai:doaj.org-article:63091e04f7cc4fa1aaff740c34dc48042021-12-02T14:40:26ZExploratory adaptation in large random networks10.1038/ncomms148262041-1723https://doaj.org/article/63091e04f7cc4fa1aaff740c34dc48042017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14826https://doaj.org/toc/2041-1723Recent works suggest that cellular networks may respond to novel challenges on the time-scale of cellular lifetimes through large-scale perturbation of gene expression and convergence to a new state. Here, the authors demonstrate the theoretical feasibility of exploratory adaptation in cellular networks by showing that convergence to new states depends on known features of these networks.Hallel I. SchreierYoav SoenNaama BrennerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hallel I. Schreier Yoav Soen Naama Brenner Exploratory adaptation in large random networks
description	Recent works suggest that cellular networks may respond to novel challenges on the time-scale of cellular lifetimes through large-scale perturbation of gene expression and convergence to a new state. Here, the authors demonstrate the theoretical feasibility of exploratory adaptation in cellular networks by showing that convergence to new states depends on known features of these networks.
format	article
author	Hallel I. Schreier Yoav Soen Naama Brenner
author_facet	Hallel I. Schreier Yoav Soen Naama Brenner
author_sort	Hallel I. Schreier
title	Exploratory adaptation in large random networks
title_short	Exploratory adaptation in large random networks
title_full	Exploratory adaptation in large random networks
title_fullStr	Exploratory adaptation in large random networks
title_full_unstemmed	Exploratory adaptation in large random networks
title_sort	exploratory adaptation in large random networks
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/63091e04f7cc4fa1aaff740c34dc4804
work_keys_str_mv	AT hallelischreier exploratoryadaptationinlargerandomnetworks AT yoavsoen exploratoryadaptationinlargerandomnetworks AT naamabrenner exploratoryadaptationinlargerandomnetworks
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Exploratory adaptation in large random networks

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