Exploratory adaptation in large random networks

Recent works suggest that cellular networks may respond to novel challenges on the time-scale of cellular lifetimes through large-scale perturbation of gene expression and convergence to a new state. Here, the authors demonstrate the theoretical feasibility of exploratory adaptation in cellular netw...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Hallel I. Schreier, Yoav Soen, Naama Brenner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/63091e04f7cc4fa1aaff740c34dc4804
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:63091e04f7cc4fa1aaff740c34dc4804
record_format dspace
spelling oai:doaj.org-article:63091e04f7cc4fa1aaff740c34dc48042021-12-02T14:40:26ZExploratory adaptation in large random networks10.1038/ncomms148262041-1723https://doaj.org/article/63091e04f7cc4fa1aaff740c34dc48042017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms14826https://doaj.org/toc/2041-1723Recent works suggest that cellular networks may respond to novel challenges on the time-scale of cellular lifetimes through large-scale perturbation of gene expression and convergence to a new state. Here, the authors demonstrate the theoretical feasibility of exploratory adaptation in cellular networks by showing that convergence to new states depends on known features of these networks.Hallel I. SchreierYoav SoenNaama BrennerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hallel I. Schreier
Yoav Soen
Naama Brenner
Exploratory adaptation in large random networks
description Recent works suggest that cellular networks may respond to novel challenges on the time-scale of cellular lifetimes through large-scale perturbation of gene expression and convergence to a new state. Here, the authors demonstrate the theoretical feasibility of exploratory adaptation in cellular networks by showing that convergence to new states depends on known features of these networks.
format article
author Hallel I. Schreier
Yoav Soen
Naama Brenner
author_facet Hallel I. Schreier
Yoav Soen
Naama Brenner
author_sort Hallel I. Schreier
title Exploratory adaptation in large random networks
title_short Exploratory adaptation in large random networks
title_full Exploratory adaptation in large random networks
title_fullStr Exploratory adaptation in large random networks
title_full_unstemmed Exploratory adaptation in large random networks
title_sort exploratory adaptation in large random networks
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/63091e04f7cc4fa1aaff740c34dc4804
work_keys_str_mv AT hallelischreier exploratoryadaptationinlargerandomnetworks
AT yoavsoen exploratoryadaptationinlargerandomnetworks
AT naamabrenner exploratoryadaptationinlargerandomnetworks
_version_ 1718390297939935232