P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5

The secretedPlasmodium falciparum protein RH5 is essential for invasion of erythrocytes and is a promising vaccine candidate. Here, Galaway et al. show that the N-terminal region of RH5 binds the GPI-anchored merozoite surface protein P113 and can elicit invasion-blocking antibodies.

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Autores principales:	Francis Galaway, Laura G. Drought, Maria Fala, Nadia Cross, Alison C. Kemp, Julian C. Rayner, Gavin J. Wright
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/63120ffd24804c9eb22499b33bf94e28
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spelling	oai:doaj.org-article:63120ffd24804c9eb22499b33bf94e282021-12-02T14:42:34ZP113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH510.1038/ncomms143332041-1723https://doaj.org/article/63120ffd24804c9eb22499b33bf94e282017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14333https://doaj.org/toc/2041-1723The secretedPlasmodium falciparum protein RH5 is essential for invasion of erythrocytes and is a promising vaccine candidate. Here, Galaway et al. show that the N-terminal region of RH5 binds the GPI-anchored merozoite surface protein P113 and can elicit invasion-blocking antibodies.Francis GalawayLaura G. DroughtMaria FalaNadia CrossAlison C. KempJulian C. RaynerGavin J. WrightNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Francis Galaway Laura G. Drought Maria Fala Nadia Cross Alison C. Kemp Julian C. Rayner Gavin J. Wright P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5
description	The secretedPlasmodium falciparum protein RH5 is essential for invasion of erythrocytes and is a promising vaccine candidate. Here, Galaway et al. show that the N-terminal region of RH5 binds the GPI-anchored merozoite surface protein P113 and can elicit invasion-blocking antibodies.
format	article
author	Francis Galaway Laura G. Drought Maria Fala Nadia Cross Alison C. Kemp Julian C. Rayner Gavin J. Wright
author_facet	Francis Galaway Laura G. Drought Maria Fala Nadia Cross Alison C. Kemp Julian C. Rayner Gavin J. Wright
author_sort	Francis Galaway
title	P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5
title_short	P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5
title_full	P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5
title_fullStr	P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5
title_full_unstemmed	P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5
title_sort	p113 is a merozoite surface protein that binds the n terminus of plasmodium falciparum rh5
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/63120ffd24804c9eb22499b33bf94e28
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P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5

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