Low-affinity CD4+ T cells are major responders in the primary immune response
MHC II tetramers are used to study T cell expansion but they preferentially bind high affinity T cell receptors. Here the authors show that T cells with low affinity receptors expand in number along with the T-cell repertoire and might therefore contribute more to the primary immune response than wa...
Guardado en:
Autores principales: | Ryan J. Martinez, Rakieb Andargachew, Hunter A. Martinez, Brian D. Evavold |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6313a9aa2c214c3d8e93fd17d0443014 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response
por: Julia Merkenschlager, et al.
Publicado: (2016) -
The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma
por: Gaetana Restivo, et al.
Publicado: (2017) -
EGR-2 is not required for in vivo CD4 T cell mediated immune responses.
por: Hilda E Ramón, et al.
Publicado: (2010) -
Publisher Correction: The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma
por: Gaetana Restivo, et al.
Publicado: (2018) -
A multi-approach and multi-scale platform to model CD4+ T cells responding to infections.
por: Kenneth Y Wertheim, et al.
Publicado: (2021)