Low-affinity CD4+ T cells are major responders in the primary immune response
MHC II tetramers are used to study T cell expansion but they preferentially bind high affinity T cell receptors. Here the authors show that T cells with low affinity receptors expand in number along with the T-cell repertoire and might therefore contribute more to the primary immune response than wa...
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| Main Authors: | , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2016
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| Subjects: | |
| Online Access: | https://doaj.org/article/6313a9aa2c214c3d8e93fd17d0443014 |
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