Strainberry: automated strain separation in low-complexity metagenomes using long reads

Existing long-read de novo assembly methods can partially, but not completely, separate strains. Here, the authors develop Strainberry, a metagenome assembly bioinformatic pipeline that exclusively uses longread data to accurately separate and reconstruct strain genomes from single-sample low-comple...

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Autores principales: Riccardo Vicedomini, Christopher Quince, Aaron E. Darling, Rayan Chikhi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6319ba8e68474bc9b3176b9f70701619
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spelling oai:doaj.org-article:6319ba8e68474bc9b3176b9f707016192021-12-02T16:17:53ZStrainberry: automated strain separation in low-complexity metagenomes using long reads10.1038/s41467-021-24515-92041-1723https://doaj.org/article/6319ba8e68474bc9b3176b9f707016192021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24515-9https://doaj.org/toc/2041-1723Existing long-read de novo assembly methods can partially, but not completely, separate strains. Here, the authors develop Strainberry, a metagenome assembly bioinformatic pipeline that exclusively uses longread data to accurately separate and reconstruct strain genomes from single-sample low-complexity microbiomes.Riccardo VicedominiChristopher QuinceAaron E. DarlingRayan ChikhiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Riccardo Vicedomini
Christopher Quince
Aaron E. Darling
Rayan Chikhi
Strainberry: automated strain separation in low-complexity metagenomes using long reads
description Existing long-read de novo assembly methods can partially, but not completely, separate strains. Here, the authors develop Strainberry, a metagenome assembly bioinformatic pipeline that exclusively uses longread data to accurately separate and reconstruct strain genomes from single-sample low-complexity microbiomes.
format article
author Riccardo Vicedomini
Christopher Quince
Aaron E. Darling
Rayan Chikhi
author_facet Riccardo Vicedomini
Christopher Quince
Aaron E. Darling
Rayan Chikhi
author_sort Riccardo Vicedomini
title Strainberry: automated strain separation in low-complexity metagenomes using long reads
title_short Strainberry: automated strain separation in low-complexity metagenomes using long reads
title_full Strainberry: automated strain separation in low-complexity metagenomes using long reads
title_fullStr Strainberry: automated strain separation in low-complexity metagenomes using long reads
title_full_unstemmed Strainberry: automated strain separation in low-complexity metagenomes using long reads
title_sort strainberry: automated strain separation in low-complexity metagenomes using long reads
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/6319ba8e68474bc9b3176b9f70701619
work_keys_str_mv AT riccardovicedomini strainberryautomatedstrainseparationinlowcomplexitymetagenomesusinglongreads
AT christopherquince strainberryautomatedstrainseparationinlowcomplexitymetagenomesusinglongreads
AT aaronedarling strainberryautomatedstrainseparationinlowcomplexitymetagenomesusinglongreads
AT rayanchikhi strainberryautomatedstrainseparationinlowcomplexitymetagenomesusinglongreads
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