The molecular basis, genetic control and pleiotropic effects of local gene co-expression

Local gene co-expression is found throughout the genome, but systematic analysis of these co-expressed genes is needed. Here, the authors identify local co-expressed genes in 49 tissues and characterize the genetic variants which may affect their expression and contribute to disease.

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Autores principales:	Diogo M. Ribeiro, Simone Rubinacci, Anna Ramisch, Robin J. Hofmeister, Emmanouil T. Dermitzakis, Olivier Delaneau
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/631aadc85a424e45a6de0ce58d753ad5
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spelling	oai:doaj.org-article:631aadc85a424e45a6de0ce58d753ad52021-12-02T19:06:43ZThe molecular basis, genetic control and pleiotropic effects of local gene co-expression10.1038/s41467-021-25129-x2041-1723https://doaj.org/article/631aadc85a424e45a6de0ce58d753ad52021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25129-xhttps://doaj.org/toc/2041-1723Local gene co-expression is found throughout the genome, but systematic analysis of these co-expressed genes is needed. Here, the authors identify local co-expressed genes in 49 tissues and characterize the genetic variants which may affect their expression and contribute to disease.Diogo M. RibeiroSimone RubinacciAnna RamischRobin J. HofmeisterEmmanouil T. DermitzakisOlivier DelaneauNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Diogo M. Ribeiro Simone Rubinacci Anna Ramisch Robin J. Hofmeister Emmanouil T. Dermitzakis Olivier Delaneau The molecular basis, genetic control and pleiotropic effects of local gene co-expression
description	Local gene co-expression is found throughout the genome, but systematic analysis of these co-expressed genes is needed. Here, the authors identify local co-expressed genes in 49 tissues and characterize the genetic variants which may affect their expression and contribute to disease.
format	article
author	Diogo M. Ribeiro Simone Rubinacci Anna Ramisch Robin J. Hofmeister Emmanouil T. Dermitzakis Olivier Delaneau
author_facet	Diogo M. Ribeiro Simone Rubinacci Anna Ramisch Robin J. Hofmeister Emmanouil T. Dermitzakis Olivier Delaneau
author_sort	Diogo M. Ribeiro
title	The molecular basis, genetic control and pleiotropic effects of local gene co-expression
title_short	The molecular basis, genetic control and pleiotropic effects of local gene co-expression
title_full	The molecular basis, genetic control and pleiotropic effects of local gene co-expression
title_fullStr	The molecular basis, genetic control and pleiotropic effects of local gene co-expression
title_full_unstemmed	The molecular basis, genetic control and pleiotropic effects of local gene co-expression
title_sort	molecular basis, genetic control and pleiotropic effects of local gene co-expression
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/631aadc85a424e45a6de0ce58d753ad5
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The molecular basis, genetic control and pleiotropic effects of local gene co-expression

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