piR-39980 mediates doxorubicin resistance in fibrosarcoma by regulating drug accumulation and DNA repair

Mallick et al. investigate the role of the piRNA, piR-39980, and doxorubicin (DOX) resistance in fibrosarcoma, finding that piR-39980 is less expressed in DOX-resistant HT1080 fibrosarcoma cells. The authors reported that its inhibition lead to attenuated intracellular DOX accumulation, DOX-indued a...

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Bibliographic Details
Main Authors: Basudeb Das, Neha Jain, Bibekanand Mallick
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Online Access:https://doaj.org/article/631ec95798a34a43b3ccb13e844cbae0
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