Fine Particulate Air Pollution and First Hospital Admissions for Ischemic Stroke in Beijing, China

Abstract The primary objective of this study was to assess the association between short-term changes in ambient fine particulate matter (PM2.5) and first hospital admissions for ischemic stroke. We identified 63,956 first hospital admissions for ischemic stroke from the Beijing Medical Claim Data f...

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Autores principales:	Yaohua Tian, Xiao Xiang, Yiqun Wu, Yaying Cao, Jing Song, Kexin Sun, Hui Liu, Yonghua Hu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6336a3691e5747a7abb0113b54b11959
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spelling	oai:doaj.org-article:6336a3691e5747a7abb0113b54b119592021-12-02T12:32:26ZFine Particulate Air Pollution and First Hospital Admissions for Ischemic Stroke in Beijing, China10.1038/s41598-017-04312-52045-2322https://doaj.org/article/6336a3691e5747a7abb0113b54b119592017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-04312-5https://doaj.org/toc/2045-2322Abstract The primary objective of this study was to assess the association between short-term changes in ambient fine particulate matter (PM2.5) and first hospital admissions for ischemic stroke. We identified 63,956 first hospital admissions for ischemic stroke from the Beijing Medical Claim Data for Employees from January 1, 2010, through June 30, 2012. A generalized additive Poisson model was applied to explore the association between PM2.5 and admissions for ischemic stroke. We also explore the effect modification of risk by age and gender. The exposure–response relationship between PM2.5 and admissions for ischemic stroke was approximately linear, with a relatively stable response at lower concentrations (<100 μg/m3) and a steeper response at higher concentrations. A 10 μg/m3 increase in the same-day PM2.5 concentration was associated with 0.31% (95% CI, 0.17–0.45%, P < 1.57 × 10−5) increase in the daily admissions for ischemic stroke. The association was also statistically significant at lag 1, 2, 3, 0–2 and 0–4 days. Subgroup analyses showed that the association was not different between patients ≥65 years and <65 years old or between males and females. In conclusion, short-term exposure to PM2.5 was positively associated with first hospital admissions for ischemic stroke in Beijing, China.Yaohua TianXiao XiangYiqun WuYaying CaoJing SongKexin SunHui LiuYonghua HuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yaohua Tian Xiao Xiang Yiqun Wu Yaying Cao Jing Song Kexin Sun Hui Liu Yonghua Hu Fine Particulate Air Pollution and First Hospital Admissions for Ischemic Stroke in Beijing, China
description	Abstract The primary objective of this study was to assess the association between short-term changes in ambient fine particulate matter (PM2.5) and first hospital admissions for ischemic stroke. We identified 63,956 first hospital admissions for ischemic stroke from the Beijing Medical Claim Data for Employees from January 1, 2010, through June 30, 2012. A generalized additive Poisson model was applied to explore the association between PM2.5 and admissions for ischemic stroke. We also explore the effect modification of risk by age and gender. The exposure–response relationship between PM2.5 and admissions for ischemic stroke was approximately linear, with a relatively stable response at lower concentrations (<100 μg/m3) and a steeper response at higher concentrations. A 10 μg/m3 increase in the same-day PM2.5 concentration was associated with 0.31% (95% CI, 0.17–0.45%, P < 1.57 × 10−5) increase in the daily admissions for ischemic stroke. The association was also statistically significant at lag 1, 2, 3, 0–2 and 0–4 days. Subgroup analyses showed that the association was not different between patients ≥65 years and <65 years old or between males and females. In conclusion, short-term exposure to PM2.5 was positively associated with first hospital admissions for ischemic stroke in Beijing, China.
format	article
author	Yaohua Tian Xiao Xiang Yiqun Wu Yaying Cao Jing Song Kexin Sun Hui Liu Yonghua Hu
author_facet	Yaohua Tian Xiao Xiang Yiqun Wu Yaying Cao Jing Song Kexin Sun Hui Liu Yonghua Hu
author_sort	Yaohua Tian
title	Fine Particulate Air Pollution and First Hospital Admissions for Ischemic Stroke in Beijing, China
title_short	Fine Particulate Air Pollution and First Hospital Admissions for Ischemic Stroke in Beijing, China
title_full	Fine Particulate Air Pollution and First Hospital Admissions for Ischemic Stroke in Beijing, China
title_fullStr	Fine Particulate Air Pollution and First Hospital Admissions for Ischemic Stroke in Beijing, China
title_full_unstemmed	Fine Particulate Air Pollution and First Hospital Admissions for Ischemic Stroke in Beijing, China
title_sort	fine particulate air pollution and first hospital admissions for ischemic stroke in beijing, china
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/6336a3691e5747a7abb0113b54b11959
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Fine Particulate Air Pollution and First Hospital Admissions for Ischemic Stroke in Beijing, China

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