Passerini-type reaction of boronic acids enables α-hydroxyketones synthesis

Multicomponent reactions enable the rapid construction of diverse molecular scaffolds with modularity and step economy. In this work, the authors report the use of boronic acids as carbon nucleophiles in a Passerini-type three-component coupling reaction towards an expanded inventory of α-hydroxyket...

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Autores principales: Kai Yang, Feng Zhang, Tongchang Fang, Chaokun Li, Wangyang Li, Qiuling Song
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/633cce68c78741b99add99a0e30b21be
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spelling oai:doaj.org-article:633cce68c78741b99add99a0e30b21be2021-12-02T14:19:04ZPasserini-type reaction of boronic acids enables α-hydroxyketones synthesis10.1038/s41467-020-20727-72041-1723https://doaj.org/article/633cce68c78741b99add99a0e30b21be2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20727-7https://doaj.org/toc/2041-1723Multicomponent reactions enable the rapid construction of diverse molecular scaffolds with modularity and step economy. In this work, the authors report the use of boronic acids as carbon nucleophiles in a Passerini-type three-component coupling reaction towards an expanded inventory of α-hydroxyketones.Kai YangFeng ZhangTongchang FangChaokun LiWangyang LiQiuling SongNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kai Yang
Feng Zhang
Tongchang Fang
Chaokun Li
Wangyang Li
Qiuling Song
Passerini-type reaction of boronic acids enables α-hydroxyketones synthesis
description Multicomponent reactions enable the rapid construction of diverse molecular scaffolds with modularity and step economy. In this work, the authors report the use of boronic acids as carbon nucleophiles in a Passerini-type three-component coupling reaction towards an expanded inventory of α-hydroxyketones.
format article
author Kai Yang
Feng Zhang
Tongchang Fang
Chaokun Li
Wangyang Li
Qiuling Song
author_facet Kai Yang
Feng Zhang
Tongchang Fang
Chaokun Li
Wangyang Li
Qiuling Song
author_sort Kai Yang
title Passerini-type reaction of boronic acids enables α-hydroxyketones synthesis
title_short Passerini-type reaction of boronic acids enables α-hydroxyketones synthesis
title_full Passerini-type reaction of boronic acids enables α-hydroxyketones synthesis
title_fullStr Passerini-type reaction of boronic acids enables α-hydroxyketones synthesis
title_full_unstemmed Passerini-type reaction of boronic acids enables α-hydroxyketones synthesis
title_sort passerini-type reaction of boronic acids enables α-hydroxyketones synthesis
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/633cce68c78741b99add99a0e30b21be
work_keys_str_mv AT kaiyang passerinitypereactionofboronicacidsenablesahydroxyketonessynthesis
AT fengzhang passerinitypereactionofboronicacidsenablesahydroxyketonessynthesis
AT tongchangfang passerinitypereactionofboronicacidsenablesahydroxyketonessynthesis
AT chaokunli passerinitypereactionofboronicacidsenablesahydroxyketonessynthesis
AT wangyangli passerinitypereactionofboronicacidsenablesahydroxyketonessynthesis
AT qiulingsong passerinitypereactionofboronicacidsenablesahydroxyketonessynthesis
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