Single cell molecular alterations reveal target cells and pathways of concussive brain injury

Traumatic brain injury (TBI) affects the hippocampus and can lead to neurological and psychiatric disorders. Here, the authors perform single-cell RNA sequencing to reveal molecular pathways across a range of cell types affected during TBI.

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Autores principales: Douglas Arneson, Guanglin Zhang, Zhe Ying, Yumei Zhuang, Hyae Ran Byun, In Sook Ahn, Fernando Gomez-Pinilla, Xia Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/633fd7ace9104ea78a460ec2ce0c46c1
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spelling oai:doaj.org-article:633fd7ace9104ea78a460ec2ce0c46c12021-12-02T16:56:37ZSingle cell molecular alterations reveal target cells and pathways of concussive brain injury10.1038/s41467-018-06222-02041-1723https://doaj.org/article/633fd7ace9104ea78a460ec2ce0c46c12018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06222-0https://doaj.org/toc/2041-1723Traumatic brain injury (TBI) affects the hippocampus and can lead to neurological and psychiatric disorders. Here, the authors perform single-cell RNA sequencing to reveal molecular pathways across a range of cell types affected during TBI.Douglas ArnesonGuanglin ZhangZhe YingYumei ZhuangHyae Ran ByunIn Sook AhnFernando Gomez-PinillaXia YangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Douglas Arneson
Guanglin Zhang
Zhe Ying
Yumei Zhuang
Hyae Ran Byun
In Sook Ahn
Fernando Gomez-Pinilla
Xia Yang
Single cell molecular alterations reveal target cells and pathways of concussive brain injury
description Traumatic brain injury (TBI) affects the hippocampus and can lead to neurological and psychiatric disorders. Here, the authors perform single-cell RNA sequencing to reveal molecular pathways across a range of cell types affected during TBI.
format article
author Douglas Arneson
Guanglin Zhang
Zhe Ying
Yumei Zhuang
Hyae Ran Byun
In Sook Ahn
Fernando Gomez-Pinilla
Xia Yang
author_facet Douglas Arneson
Guanglin Zhang
Zhe Ying
Yumei Zhuang
Hyae Ran Byun
In Sook Ahn
Fernando Gomez-Pinilla
Xia Yang
author_sort Douglas Arneson
title Single cell molecular alterations reveal target cells and pathways of concussive brain injury
title_short Single cell molecular alterations reveal target cells and pathways of concussive brain injury
title_full Single cell molecular alterations reveal target cells and pathways of concussive brain injury
title_fullStr Single cell molecular alterations reveal target cells and pathways of concussive brain injury
title_full_unstemmed Single cell molecular alterations reveal target cells and pathways of concussive brain injury
title_sort single cell molecular alterations reveal target cells and pathways of concussive brain injury
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/633fd7ace9104ea78a460ec2ce0c46c1
work_keys_str_mv AT douglasarneson singlecellmolecularalterationsrevealtargetcellsandpathwaysofconcussivebraininjury
AT guanglinzhang singlecellmolecularalterationsrevealtargetcellsandpathwaysofconcussivebraininjury
AT zheying singlecellmolecularalterationsrevealtargetcellsandpathwaysofconcussivebraininjury
AT yumeizhuang singlecellmolecularalterationsrevealtargetcellsandpathwaysofconcussivebraininjury
AT hyaeranbyun singlecellmolecularalterationsrevealtargetcellsandpathwaysofconcussivebraininjury
AT insookahn singlecellmolecularalterationsrevealtargetcellsandpathwaysofconcussivebraininjury
AT fernandogomezpinilla singlecellmolecularalterationsrevealtargetcellsandpathwaysofconcussivebraininjury
AT xiayang singlecellmolecularalterationsrevealtargetcellsandpathwaysofconcussivebraininjury
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