A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment
Abstract Cancer-associated fibroblasts (CAFs) are one of the most prominent cell types in the stromal compartment of the tumor microenvironment. CAFs support multiple aspects of cancer progression, including tumor initiation, invasion, and metastasis. The heterogeneous nature of the stromal microenv...
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Main Authors: | , , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Subjects: | |
Online Access: | https://doaj.org/article/63542ceb2b9e4c0181ab0651968d562c |
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