Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival

Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival

Surface-enhanced Raman spectroscopy (SERS) visualizes fingerprints of intermolecular vibrations of many metabolites. Here the authors report a SERS imaging technique that enables the visualization of metabolites distribution and automated extraction of tumour boundaries in frozen tissues.

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Autores principales: Megumi Shiota, Masayuki Naya, Takehiro Yamamoto, Takako Hishiki, Takeharu Tani, Hiroyuki Takahashi, Akiko Kubo, Daisuke Koike, Mai Itoh, Mitsuyo Ohmura, Yasuaki Kabe, Yuki Sugiura, Nobuyoshi Hiraoka, Takayuki Morikawa, Keiyo Takubo, Kentaro Suina, Hideaki Nagashima, Oltea Sampetrean, Osamu Nagano, Hideyuki Saya, Shogo Yamazoe, Hiroyuki Watanabe, Makoto Suematsu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Q
Acceso en línea:https://doaj.org/article/6370f21a7dce45e4b681376a2ad703d3
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spelling oai:doaj.org-article:6370f21a7dce45e4b681376a2ad703d32021-12-02T14:40:31ZGold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival10.1038/s41467-018-03899-12041-1723https://doaj.org/article/6370f21a7dce45e4b681376a2ad703d32018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03899-1https://doaj.org/toc/2041-1723Surface-enhanced Raman spectroscopy (SERS) visualizes fingerprints of intermolecular vibrations of many metabolites. Here the authors report a SERS imaging technique that enables the visualization of metabolites distribution and automated extraction of tumour boundaries in frozen tissues.Megumi ShiotaMasayuki NayaTakehiro YamamotoTakako HishikiTakeharu TaniHiroyuki TakahashiAkiko KuboDaisuke KoikeMai ItohMitsuyo OhmuraYasuaki KabeYuki SugiuraNobuyoshi HiraokaTakayuki MorikawaKeiyo TakuboKentaro SuinaHideaki NagashimaOltea SampetreanOsamu NaganoHideyuki SayaShogo YamazoeHiroyuki WatanabeMakoto SuematsuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Megumi Shiota
Masayuki Naya
Takehiro Yamamoto
Takako Hishiki
Takeharu Tani
Hiroyuki Takahashi
Akiko Kubo
Daisuke Koike
Mai Itoh
Mitsuyo Ohmura
Yasuaki Kabe
Yuki Sugiura
Nobuyoshi Hiraoka
Takayuki Morikawa
Keiyo Takubo
Kentaro Suina
Hideaki Nagashima
Oltea Sampetrean
Osamu Nagano
Hideyuki Saya
Shogo Yamazoe
Hiroyuki Watanabe
Makoto Suematsu
Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival
description Surface-enhanced Raman spectroscopy (SERS) visualizes fingerprints of intermolecular vibrations of many metabolites. Here the authors report a SERS imaging technique that enables the visualization of metabolites distribution and automated extraction of tumour boundaries in frozen tissues.
format article
author Megumi Shiota
Masayuki Naya
Takehiro Yamamoto
Takako Hishiki
Takeharu Tani
Hiroyuki Takahashi
Akiko Kubo
Daisuke Koike
Mai Itoh
Mitsuyo Ohmura
Yasuaki Kabe
Yuki Sugiura
Nobuyoshi Hiraoka
Takayuki Morikawa
Keiyo Takubo
Kentaro Suina
Hideaki Nagashima
Oltea Sampetrean
Osamu Nagano
Hideyuki Saya
Shogo Yamazoe
Hiroyuki Watanabe
Makoto Suematsu
author_facet Megumi Shiota
Masayuki Naya
Takehiro Yamamoto
Takako Hishiki
Takeharu Tani
Hiroyuki Takahashi
Akiko Kubo
Daisuke Koike
Mai Itoh
Mitsuyo Ohmura
Yasuaki Kabe
Yuki Sugiura
Nobuyoshi Hiraoka
Takayuki Morikawa
Keiyo Takubo
Kentaro Suina
Hideaki Nagashima
Oltea Sampetrean
Osamu Nagano
Hideyuki Saya
Shogo Yamazoe
Hiroyuki Watanabe
Makoto Suematsu
author_sort Megumi Shiota
title Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival
title_short Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival
title_full Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival
title_fullStr Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival
title_full_unstemmed Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival
title_sort gold-nanofève surface-enhanced raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/6370f21a7dce45e4b681376a2ad703d3
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