Tetrameric architecture of an active phenol-bound form of the AAA+ transcriptional regulator DmpR

DmpR is a bacterial enhancer binding protein from the AAA+ family of ATPases that binds aromatic compounds and controls the transcription of genes involved in the degradation of toxic pollutants. Here, the authors present the crystal structure of phenol-bound DmpR, which forms a tetramer and discuss...

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Autores principales:	Kwang-Hyun Park, Sungchul Kim, Su-Jin Lee, Jee-Eun Cho, Vinod Vikas Patil, Arti Baban Dumbrepatil, Hyung-Nam Song, Woo-Chan Ahn, Chirlmin Joo, Seung-Goo Lee, Victoria Shingler, Eui-Jeon Woo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6374ad5a606946a1a3d3d128d4b36abf
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spelling	oai:doaj.org-article:6374ad5a606946a1a3d3d128d4b36abf2021-12-02T18:24:49ZTetrameric architecture of an active phenol-bound form of the AAA+ transcriptional regulator DmpR10.1038/s41467-020-16562-52041-1723https://doaj.org/article/6374ad5a606946a1a3d3d128d4b36abf2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16562-5https://doaj.org/toc/2041-1723DmpR is a bacterial enhancer binding protein from the AAA+ family of ATPases that binds aromatic compounds and controls the transcription of genes involved in the degradation of toxic pollutants. Here, the authors present the crystal structure of phenol-bound DmpR, which forms a tetramer and discuss its signal transduction mechanism.Kwang-Hyun ParkSungchul KimSu-Jin LeeJee-Eun ChoVinod Vikas PatilArti Baban DumbrepatilHyung-Nam SongWoo-Chan AhnChirlmin JooSeung-Goo LeeVictoria ShinglerEui-Jeon WooNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kwang-Hyun Park Sungchul Kim Su-Jin Lee Jee-Eun Cho Vinod Vikas Patil Arti Baban Dumbrepatil Hyung-Nam Song Woo-Chan Ahn Chirlmin Joo Seung-Goo Lee Victoria Shingler Eui-Jeon Woo Tetrameric architecture of an active phenol-bound form of the AAA+ transcriptional regulator DmpR
description	DmpR is a bacterial enhancer binding protein from the AAA+ family of ATPases that binds aromatic compounds and controls the transcription of genes involved in the degradation of toxic pollutants. Here, the authors present the crystal structure of phenol-bound DmpR, which forms a tetramer and discuss its signal transduction mechanism.
format	article
author	Kwang-Hyun Park Sungchul Kim Su-Jin Lee Jee-Eun Cho Vinod Vikas Patil Arti Baban Dumbrepatil Hyung-Nam Song Woo-Chan Ahn Chirlmin Joo Seung-Goo Lee Victoria Shingler Eui-Jeon Woo
author_facet	Kwang-Hyun Park Sungchul Kim Su-Jin Lee Jee-Eun Cho Vinod Vikas Patil Arti Baban Dumbrepatil Hyung-Nam Song Woo-Chan Ahn Chirlmin Joo Seung-Goo Lee Victoria Shingler Eui-Jeon Woo
author_sort	Kwang-Hyun Park
title	Tetrameric architecture of an active phenol-bound form of the AAA+ transcriptional regulator DmpR
title_short	Tetrameric architecture of an active phenol-bound form of the AAA+ transcriptional regulator DmpR
title_full	Tetrameric architecture of an active phenol-bound form of the AAA+ transcriptional regulator DmpR
title_fullStr	Tetrameric architecture of an active phenol-bound form of the AAA+ transcriptional regulator DmpR
title_full_unstemmed	Tetrameric architecture of an active phenol-bound form of the AAA+ transcriptional regulator DmpR
title_sort	tetrameric architecture of an active phenol-bound form of the aaa+ transcriptional regulator dmpr
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6374ad5a606946a1a3d3d128d4b36abf
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Tetrameric architecture of an active phenol-bound form of the AAA+ transcriptional regulator DmpR

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