Relevance of SYNTAX score for assessment of saphenous vein graft failure after coronary artery bypass grafting

Objective: To identify risk factors of saphenous vein graft (SVG) failure and to investigate the utility of anatomical SYNTAX score (SS) and SYNTAX score II (SS-II) in predicting SVG failure. Methods: A total of 598 patients who underwent angiography for clinical reasons after coronary artery bypass...

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Autores principales: Jia-Hui Li, Xian-Tao Song, Xue-Yao Yang, Wen-Yi Zhang, Hao-Ran Xing
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Publicado: KeAi Communications Co., Ltd. 2020
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spelling oai:doaj.org-article:63758e02bfd2450a8a8c79254e321e452021-12-02T14:10:37ZRelevance of SYNTAX score for assessment of saphenous vein graft failure after coronary artery bypass grafting2095-882X10.1016/j.cdtm.2019.05.005https://doaj.org/article/63758e02bfd2450a8a8c79254e321e452020-03-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095882X19300295https://doaj.org/toc/2095-882XObjective: To identify risk factors of saphenous vein graft (SVG) failure and to investigate the utility of anatomical SYNTAX score (SS) and SYNTAX score II (SS-II) in predicting SVG failure. Methods: A total of 598 patients who underwent angiography for clinical reasons after coronary artery bypass grafting (CABG) were included. Baseline data and factors related to SVG failure were analyzed at the patient and graft levels. Patients were divided in tertiles by anatomical SS and in three groups by SS-II revascularization recommendation, and SVG patency was analyzed across these groups. Results: Patency rates were similar in all SS-stratified and SS-II recommendation groups within 1, 5, and 10 years after CABG. At the patient level, fasting blood glucose (FBG) level <7.0 mmol/L was less common in SVG failure (68.0% vs. 76.2%). At the graft level, patients with SVG failure tended to have angiography later (4.0 years vs. 3.0 years), poorer FBG control (FBG <7.0 mmol/L: 68.2% vs. 74.7%), and more grafts anastomosed to the right coronary system (59.2% vs. 47.4%). Longer time interval after CABG was related to SVG failure both at the patient and graft levels, and odds ratio (OR)/P values (OR/P) were 1.282/0.029 and 1.384/0.016, respectively. Using independent graft and grafting to the right artery system as risk factors at the graft level, OR/Ps were 3.094/0.000 and 2.524/0.000, respectively. Conclusions: Longer time interval after CABG, independent grafts, and grafting to the right artery system are associated with SVG failure. Anatomical SS or SS-II may not be reasonable tools for predicting SVG failure. Keywords: Coronary artery bypass grafting, Graft patency, Saphenous vein graft, SYNTAX score, PredictorJia-Hui LiXian-Tao SongXue-Yao YangWen-Yi ZhangHao-Ran XingKeAi Communications Co., Ltd.articleMedicine (General)R5-920ENChronic Diseases and Translational Medicine, Vol 6, Iss 1, Pp 55-61 (2020)
institution DOAJ
collection DOAJ
language EN
topic Medicine (General)
R5-920
spellingShingle Medicine (General)
R5-920
Jia-Hui Li
Xian-Tao Song
Xue-Yao Yang
Wen-Yi Zhang
Hao-Ran Xing
Relevance of SYNTAX score for assessment of saphenous vein graft failure after coronary artery bypass grafting
description Objective: To identify risk factors of saphenous vein graft (SVG) failure and to investigate the utility of anatomical SYNTAX score (SS) and SYNTAX score II (SS-II) in predicting SVG failure. Methods: A total of 598 patients who underwent angiography for clinical reasons after coronary artery bypass grafting (CABG) were included. Baseline data and factors related to SVG failure were analyzed at the patient and graft levels. Patients were divided in tertiles by anatomical SS and in three groups by SS-II revascularization recommendation, and SVG patency was analyzed across these groups. Results: Patency rates were similar in all SS-stratified and SS-II recommendation groups within 1, 5, and 10 years after CABG. At the patient level, fasting blood glucose (FBG) level <7.0 mmol/L was less common in SVG failure (68.0% vs. 76.2%). At the graft level, patients with SVG failure tended to have angiography later (4.0 years vs. 3.0 years), poorer FBG control (FBG <7.0 mmol/L: 68.2% vs. 74.7%), and more grafts anastomosed to the right coronary system (59.2% vs. 47.4%). Longer time interval after CABG was related to SVG failure both at the patient and graft levels, and odds ratio (OR)/P values (OR/P) were 1.282/0.029 and 1.384/0.016, respectively. Using independent graft and grafting to the right artery system as risk factors at the graft level, OR/Ps were 3.094/0.000 and 2.524/0.000, respectively. Conclusions: Longer time interval after CABG, independent grafts, and grafting to the right artery system are associated with SVG failure. Anatomical SS or SS-II may not be reasonable tools for predicting SVG failure. Keywords: Coronary artery bypass grafting, Graft patency, Saphenous vein graft, SYNTAX score, Predictor
format article
author Jia-Hui Li
Xian-Tao Song
Xue-Yao Yang
Wen-Yi Zhang
Hao-Ran Xing
author_facet Jia-Hui Li
Xian-Tao Song
Xue-Yao Yang
Wen-Yi Zhang
Hao-Ran Xing
author_sort Jia-Hui Li
title Relevance of SYNTAX score for assessment of saphenous vein graft failure after coronary artery bypass grafting
title_short Relevance of SYNTAX score for assessment of saphenous vein graft failure after coronary artery bypass grafting
title_full Relevance of SYNTAX score for assessment of saphenous vein graft failure after coronary artery bypass grafting
title_fullStr Relevance of SYNTAX score for assessment of saphenous vein graft failure after coronary artery bypass grafting
title_full_unstemmed Relevance of SYNTAX score for assessment of saphenous vein graft failure after coronary artery bypass grafting
title_sort relevance of syntax score for assessment of saphenous vein graft failure after coronary artery bypass grafting
publisher KeAi Communications Co., Ltd.
publishDate 2020
url https://doaj.org/article/63758e02bfd2450a8a8c79254e321e45
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