Changes in visual function and thickness of macula after photodynamic therapy for age-related macular degeneration

Kyoko Okada, Mariko Kubota-Taniai, Masayasu Kitahashi, Takayuki Baba, Yoshinori Mitamura, Shuichi YamamotoDepartment of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, JapanPurpose: To determine the correlation between the changes in the central retinal sensiti...

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Autores principales:	Kyoko Okada, Mariko Kubota-Taniai, Masayasu Kitahashi, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2009
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/637a5cf0f271486f86ebe362b1af844d
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spelling	oai:doaj.org-article:637a5cf0f271486f86ebe362b1af844d2021-12-02T07:59:06ZChanges in visual function and thickness of macula after photodynamic therapy for age-related macular degeneration1177-54671177-5483https://doaj.org/article/637a5cf0f271486f86ebe362b1af844d2009-09-01T00:00:00Zhttp://www.dovepress.com/changes-in-visual-function-and-thickness-of-macula-after-photodynamic--a3504https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Kyoko Okada, Mariko Kubota-Taniai, Masayasu Kitahashi, Takayuki Baba, Yoshinori Mitamura, Shuichi YamamotoDepartment of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, JapanPurpose: To determine the correlation between the changes in the central retinal sensitivity and the changes in the foveal thickness (FT) after photodynamic therapy (PDT) for age-related macular degeneration (AMD).Methods: Nineteen eyes of 19 patients with choroidal neovasularizations (CNVs) secondary to AMD were studied. The pretreatment values of the central retinal sensitivity determined by Micro Perimeter 1 (MP1; Nidek Technologies), best-corrected visual acuity (BCVA), and optical coherence tomography (OCT)-determined FT were compared to the postoperative values at three and six months after PDT.Results: At six months, the retinal sensitivity within the central 10&deg; was significantly improved (P = 0.02) and the FT was significantly thinner (P = 0.016). The BCVA, however, did not change significantly (P = 0.80). The changes in the retinal sensitivities were significantly correlated with the changes in the decrease in the FT (r = -0.59, P = 0.012 within the central 10&deg;) at six months after PDT.Conclusion: Significant improvements in retinal sensitivities within the central 10&deg; and a decrease in FT were observed even though the BCVA was not significantly improved. The measurement of retinal sensitivity by MP1 may be a better method to assess central visual function than the conventional visual acuity after PDT.Keywords: age-related macular degeneration, fundus-related microperimetry, optical coherence tomography, photodynamic therapy Kyoko OkadaMariko Kubota-TaniaiMasayasu Kitahashiet alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2009, Iss default, Pp 483-488 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Kyoko Okada Mariko Kubota-Taniai Masayasu Kitahashi et al Changes in visual function and thickness of macula after photodynamic therapy for age-related macular degeneration
description	Kyoko Okada, Mariko Kubota-Taniai, Masayasu Kitahashi, Takayuki Baba, Yoshinori Mitamura, Shuichi YamamotoDepartment of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, JapanPurpose: To determine the correlation between the changes in the central retinal sensitivity and the changes in the foveal thickness (FT) after photodynamic therapy (PDT) for age-related macular degeneration (AMD).Methods: Nineteen eyes of 19 patients with choroidal neovasularizations (CNVs) secondary to AMD were studied. The pretreatment values of the central retinal sensitivity determined by Micro Perimeter 1 (MP1; Nidek Technologies), best-corrected visual acuity (BCVA), and optical coherence tomography (OCT)-determined FT were compared to the postoperative values at three and six months after PDT.Results: At six months, the retinal sensitivity within the central 10&deg; was significantly improved (P = 0.02) and the FT was significantly thinner (P = 0.016). The BCVA, however, did not change significantly (P = 0.80). The changes in the retinal sensitivities were significantly correlated with the changes in the decrease in the FT (r = -0.59, P = 0.012 within the central 10&deg;) at six months after PDT.Conclusion: Significant improvements in retinal sensitivities within the central 10&deg; and a decrease in FT were observed even though the BCVA was not significantly improved. The measurement of retinal sensitivity by MP1 may be a better method to assess central visual function than the conventional visual acuity after PDT.Keywords: age-related macular degeneration, fundus-related microperimetry, optical coherence tomography, photodynamic therapy
format	article
author	Kyoko Okada Mariko Kubota-Taniai Masayasu Kitahashi et al
author_facet	Kyoko Okada Mariko Kubota-Taniai Masayasu Kitahashi et al
author_sort	Kyoko Okada
title	Changes in visual function and thickness of macula after photodynamic therapy for age-related macular degeneration
title_short	Changes in visual function and thickness of macula after photodynamic therapy for age-related macular degeneration
title_full	Changes in visual function and thickness of macula after photodynamic therapy for age-related macular degeneration
title_fullStr	Changes in visual function and thickness of macula after photodynamic therapy for age-related macular degeneration
title_full_unstemmed	Changes in visual function and thickness of macula after photodynamic therapy for age-related macular degeneration
title_sort	changes in visual function and thickness of macula after photodynamic therapy for age-related macular degeneration
publisher	Dove Medical Press
publishDate	2009
url	https://doaj.org/article/637a5cf0f271486f86ebe362b1af844d
work_keys_str_mv	AT kyokookada changesinvisualfunctionandthicknessofmaculaafterphotodynamictherapyforagerelatedmaculardegeneration AT marikokubotataniai changesinvisualfunctionandthicknessofmaculaafterphotodynamictherapyforagerelatedmaculardegeneration AT masayasukitahashi changesinvisualfunctionandthicknessofmaculaafterphotodynamictherapyforagerelatedmaculardegeneration AT etal changesinvisualfunctionandthicknessofmaculaafterphotodynamictherapyforagerelatedmaculardegeneration
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Changes in visual function and thickness of macula after photodynamic therapy for age-related macular degeneration

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