Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice

How structural features on oocytes regulate mammalian female reproduction is unclear. Here, the authors provide imaging and physiological evidence (for example on Radixin knockout) to identify oocyte-derived mushroom-like microvilli that control the female reproductive lifespan by governing the fate...

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Autores principales:	Yan Zhang, Ye Wang, Xie’an Feng, Shuo Zhang, Xueqiang Xu, Lingyu Li, Shudong Niu, Yingnan Bo, Chao Wang, Zhen Li, Guoliang Xia, Hua Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/638000cff18441019437acafe4c03b06
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spelling	oai:doaj.org-article:638000cff18441019437acafe4c03b062021-12-02T14:49:22ZOocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice10.1038/s41467-021-22829-22041-1723https://doaj.org/article/638000cff18441019437acafe4c03b062021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22829-2https://doaj.org/toc/2041-1723How structural features on oocytes regulate mammalian female reproduction is unclear. Here, the authors provide imaging and physiological evidence (for example on Radixin knockout) to identify oocyte-derived mushroom-like microvilli that control the female reproductive lifespan by governing the fate of follicles.Yan ZhangYe WangXie’an FengShuo ZhangXueqiang XuLingyu LiShudong NiuYingnan BoChao WangZhen LiGuoliang XiaHua ZhangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yan Zhang Ye Wang Xie’an Feng Shuo Zhang Xueqiang Xu Lingyu Li Shudong Niu Yingnan Bo Chao Wang Zhen Li Guoliang Xia Hua Zhang Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice
description	How structural features on oocytes regulate mammalian female reproduction is unclear. Here, the authors provide imaging and physiological evidence (for example on Radixin knockout) to identify oocyte-derived mushroom-like microvilli that control the female reproductive lifespan by governing the fate of follicles.
format	article
author	Yan Zhang Ye Wang Xie’an Feng Shuo Zhang Xueqiang Xu Lingyu Li Shudong Niu Yingnan Bo Chao Wang Zhen Li Guoliang Xia Hua Zhang
author_facet	Yan Zhang Ye Wang Xie’an Feng Shuo Zhang Xueqiang Xu Lingyu Li Shudong Niu Yingnan Bo Chao Wang Zhen Li Guoliang Xia Hua Zhang
author_sort	Yan Zhang
title	Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice
title_short	Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice
title_full	Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice
title_fullStr	Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice
title_full_unstemmed	Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice
title_sort	oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/638000cff18441019437acafe4c03b06
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Oocyte-derived microvilli control female fertility by optimizing ovarian follicle selection in mice

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