Profiling the dynamics of a human phosphorylome reveals new components in HGF/c-Met signaling.

Protein phosphorylation is a dynamic and reversible event that greatly influences cellular function. Identifying the key regulatory elements that determine cellular phenotypes during development and oncogenesis requires the ability to dynamically monitor proteome-wide events. Here, we report the dev...

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Autores principales: Crystal L Woodard, C Rory Goodwin, Jun Wan, Shuli Xia, Robert Newman, Jianfei Hu, Jin Zhang, S Diane Hayward, Jiang Qian, John Laterra, Heng Zhu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/638242fc6a6f4262a2da615d0a3467af
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