IPA-3 inhibits the growth of liver cancer cells by suppressing PAK1 and NF-κB activation.

IPA-3 inhibits the growth of liver cancer cells by suppressing PAK1 and NF-κB activation.

Hepatocellular carcinoma (HCC) is one of the major malignancies worldwide and is associated with poor prognosis due to the high incidences of metastasis and tumor recurrence. Our previous study showed that overexpression of p21-activated protein kinase 1 (PAK1) is frequently observed in HCC and is a...

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Autores principales: Leo Lap-Yan Wong, Ian Pak-Yan Lam, Tracy Yuk-Nar Wong, Wai-Lung Lai, Heong-Fai Liu, Lam-Lung Yeung, Yick-Pang Ching
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/6383f5cc11c94fa0bf05753f7bce7372
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