Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein
ABSTRACT CRISPR (clustered regularly interspaced short palindromic repeat)-Cas adaptive immune systems are prevalent defense mechanisms in bacteria and archaea. They provide sequence-specific detection and neutralization of foreign nucleic acids such as bacteriophages and plasmids. One mechanism by...
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Main Authors: | April Pawluk, Megha Shah, Marios Mejdani, Charles Calmettes, Trevor F. Moraes, Alan R. Davidson, Karen L. Maxwell |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2017
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Online Access: | https://doaj.org/article/638a3e556a714bbc9c1150d62a69a2df |
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